7 Result(s)

Article

Enrichment of high-grade tumors in breast cancer gene expression studies

Gene expression (GE) profiling for breast cancer classification and prognostication has become increasingly used in clinical diagnostics. GE profiling requires a reasonable tumor cell percentage and high-quali...

M. van Seijen, A. L. Mooyaart, L. Mulder… in Breast Cancer Research and Treatment (2018)

Article

Erratum to: Gene expression profiling to predict the risk of locoregional recurrence in breast cancer: a pooled analysis

C. A. Drukker, S. G. Elias, M. V. Nijenhuis… in Breast Cancer Research and Treatment (2015)

Article

Optimized outcome prediction in breast cancer by combining the 70-gene signature with clinical risk prediction algorithms

Clinical guidelines for breast cancer treatment differ in their selection of patients at a high risk of recurrence who are eligible to receive adjuvant systemic treatment (AST). The 70-gene signature is a mole...

C. A. Drukker, M. V. Nijenhuis… in Breast Cancer Research and Treatment (2014)

Article

Long-term impact of the 70-gene signature on breast cancer outcome

Several studies have validated the prognostic value of the 70-gene prognosis signature (MammaPrint^R), but long-term outcome prediction of these patients has not been previously reported. The follow-up of the cons...

C. A. Drukker, H. van Tinteren, M. K. Schmidt… in Breast Cancer Research and Treatment (2014)

Article

Mammographic screening detects low-risk tumor biology breast cancers

Overdiagnosis of breast cancer, i.e. the detection of slow-growing tumors that would never have caused symptoms or death, became more prevalent with the implementation of population-based screening. Only rough...

C. A. Drukker, M. K. Schmidt, E. J. T. Rutgers… in Breast Cancer Research and Treatment (2014)