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  1. Article

    Open Access

    Methodological guidance for the evaluation and updating of clinical prediction models: a systematic review

    Clinical prediction models are often not evaluated properly in specific settings or updated, for instance, with information from new markers. These key steps are needed such that models are fit for purpose and...

    M. A. E. Binuya, E. G. Engelhardt, W. Schats… in BMC Medical Research Methodology (2022)

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  2. Article

    Open Access

    Decision support systems for incurable non-small cell lung cancer: a systematic review

    Individually tailored cancer treatment is essential to ensure optimal treatment and resource use. Treatments for incurable metastatic non-small cell lung cancer (NSCLC) are evolving rapidly, and decision suppo...

    D. Révész, E. G. Engelhardt, J. J. Tamminga… in BMC Medical Informatics and Decision Making (2017)

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  3. Article

    Open Access

    Timing of risk reducing mastectomy in breast cancer patients carrying a BRCA1/2 mutation: retrospective data from the Dutch HEBON study

    It is expected that rapid genetic counseling and testing (RGCT) will lead to increasing numbers of breast cancer (BC) patients knowing their BRCA1/2 carrier status before primary surgery. Considering the potentia...

    M. R. Wevers, M. K. Schmidt, E. G. Engelhardt, S. Verhoef, M. J. Hooning… in Familial Cancer (2015)

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