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Article
Open AccessThe p38α mitogen-activated protein kinase is a key regulator of myelination and remyelination in the CNS
The p38α mitogen-activated protein kinase (MAPK) is one of the serine/threonine kinases regulating a variety of biological processes, including cell-type specification, differentiation and migration. Previous in ...
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Article
Erratum: The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2009)
Correction to: Hypertension Research (2009) 32, 3–107; doi:10.1038/hr.2008.15, doi:10.1038/hr.2008.10, doi:10.1038/hr.2008.11 In response to the interim report on the Shiga Microalbuminuria Reduction Trial (SM...
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Article
A message from the new Editor-in-Chief
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Chapter and Conference Paper
Noise Measurement Results of Shinkansen High-Speed Test Train (FASTECH360S,Z)
East Japan Railway Company has developed the high-speed test train “FASTECH360” for future speed-increase of the Shinkansen. Noise reduction is one of the most important issues to be resolved in such a case. T...
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Article
Preparation of new inorganic–organic complexes by using FexTi1−2xNb1+xO 5 − (x = 0–0.5) nanosheets
Novel inorganic–organic complex nanocomposites have been prepared by using exfoliated FexTi1−2xNb1+xO 5 − nanosheets and poly (N-octadecyl-2-ethynyl pyridinium...
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Article
Magnetic field effect on electron transfer reactions of flavin derivatives associated with micelles
The magnetic field effects (MFEs) on the electron transfer reactions from indole derivatives to flavin derivatives in micellar solutions are studied. The MFEs on the free radical yields observed by transient a...
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Chapter
Citrin deficiency
Citrin is a mitochondrial aspartate/glutamate carrier whose deficiency causes adult-onset type II citrullinemia (CTLN2; OMIM #603471) and neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD; O...
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Article
Transcription factor decoy for NFκB inhibits TNF-α-induced cytokine and adhesion molecule expression in vivo
The expression of several cytokines and adhesion molecules is regulated by the transcription factor NFκB, which is activated by tumor necrosis factor alpha (TNF-α). In this study, we employed a mouse model of ...
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Chapter
A study on the adaptability mechanism of tree roots on steep slopes
Woody vegetation affects the stability of steep mountain slopes mainly by increasing the shear strength of soil via root reinforcement. Plant roots on steep terrain tend to elongate uphill. As the slope angle inc...
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Article
Immunohistochemical study of some cytoskeletal proteins in hereditary myopathy of the diaphragmatic muscles in Holstein-Friesian cattle
We have investigated the expression, using immunohistochemical and Western blot methods, of some cytoskeletal proteins including desmin, vimentin, actin, α-actinin, and ubiquitin in hereditary myopathy of the...
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Article
Detection methods of possible prion contaminants in collagen and gelatin
We describe methods for the preparation of collagen and gelatin samples to detect possible prion contaminants using Western blotting of a major component of prions, PrPSc. A commercially available collagen soluti...
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Article
Primary radiotherapy for tongue cancers with a tumor thickness exceeding 1 cm
Background. In tongue cancers with a tumor thickness exceeding 1 cm, the validity of radiotherapy as an initial treatment remains controversial.
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Article
Secondary defects in low-energy As-implanted Si
/cm2 dose of As ions followed by both isochronal and isothermal annealing. The elementary defects generated first during solid-phase epitaxial recovery of implantation-induced amorphous layers at temperatures of...
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Article
Recrystallization of Si-, As- And BF2-Implanted, Bonded SOI
Conventional and high-resolution cross-sectional TEM observations have been carried out on Si-, As- and BF2-implanted, bonded 100-nm-thick (001) SOI layers having polycrystalline Si (poly-Si) masks followed by an...
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Article
Improvement of PrPSc-detection in mouse spleen early at the preclinical stage of scrapie with collagenase-completed tissue homogenization and Sarkosyl-NaCl extraction of PrPSc
Scrapie in sheep has recently become again a target of control measures and eradication programs. Crucial for the effectiveness of these measures is the detection of infected sheep during the long and potentia...
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Article
Bovine herpesvirus meningoencephalitis association with infectious bovine rhinotracheitis (IBR) vaccine
During 1992, on a farm in the Tokachi district of Hokkaido, Japan, approximately 20 Holstein-Friesian calves showed neuroparalysis and died within 7–10 days after routine vaccination. Six male calves, aged abo...
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Article
Expression cloning of type 2 angiotensin II receptor reveals a unique class of seven-transmembrane receptors
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Article
Map** of jvs (juvenile visceral steatosis) gene, which causes systemic carnitine deficiency in mice, on Chromosome 11
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Article
Mitochondrial abnormalities of muscle tissue in mice with juvenile visceral steatosis associated with systemic carnitine deficiency
A mouse with juvenile visceral steatosis (the JVS mouse) has been recognized as a novel animal model for systemic carnitine deficiency. We examined cardiac, skeletal and smooth muscle cells in JVS and control ...
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Article
Detection of PrPSc in sheep at the preclinical stage of scrapie and its significance for diagnosis of insidious infection
A field sheep insidiously infected with natural scrapie was diagnosed at the preclinical stage through detection of the core fragment of PrpSc (PrPcore) in peripheral lymph nodes by the biopsy method. Three out o...