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Article
A New View of Stem Cell Dynamics
Our understanding of the biology of hematopoietic stem cells is evolving beyond hierarchical models and markers of stem cell purification to a far more fluid model wherein degrees of multipotency of individual...
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Chapter
Extracellular Vesicles and Tissue Organ Regeneration
Marrow cells are a rich source of vesicles (released from their surface or endosomal compartment that may deliver proteins, ribonucleic acid (RNA), and microRNA (miRNA) into damaged organs. Based on this, para...
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Article
The stem cell continuum
Traditional models of hematopoiesis have been hierarchical. Recent evidence showing that marrow stem cells are a cycling population and that the hematopoietic phenotype of these cells reversibly changes with c...
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Article
The marrow stem cell: the continuum
The marrow hematopoietic stem cell is currently being redefined as to all aspects of its phenotype and its total differentiation capacity. This redefinition now includes its plasticity as to production of nonh...