6 Result(s)
within
Luke M. Evans
Human Genetics
-
Article
Open AccessWithin-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects
Estimates from genome-wide association studies (GWAS) of unrelated individuals capture effects of inherited variation (direct effects), demography (population stratification, assortative mating) and relatives ...
-
Article
Characterization of a large sex determination region in Salix purpurea L. (Salicaceae)
Dioecy has evolved numerous times in plants, but heteromorphic sex chromosomes are apparently rare. Sex determination has been studied in multiple Salix and Populus (Salicaceae) species, and P. trichocarpa has an...
-
Article
Narrow-sense heritability estimation of complex traits using identity-by-descent information
Heritability is a fundamental parameter in genetics. Traditional estimates based on family or twin studies can be biased due to shared environmental or non-additive genetic variance. Alternatively, those based...
-
Article
Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits
Multiple methods have been developed to estimate narrow-sense heritability, h2, using single nucleotide polymorphisms (SNPs) in unrelated individuals. However, a comprehensive evaluation of these methods has not ...
-
Article
Using partitioned heritability methods to explore genetic architecture
-
Article
Population genomics of Populus trichocarpa identifies signatures of selection and adaptive trait associations
Stephen DiFazio and colleagues report the genome sequences and population genomic analyses of 544 black cottonwood trees (Populus trichocarpa) along the Northwest coast of North America. They find evidence for cl...
