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Open AccessAuthor Correction: Intratumoural immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21556-y.
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Article
Open AccessIntratumoural immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma
The clinical relevance of immune landscape intratumoural heterogeneity (immune-ITH) and its role in tumour evolution remain largely unexplored. Here, we uncover significant spatial and phenotypic immune-ITH fr...
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Article
Open AccessImpact of Michaelis–Menten type harvesting in a Lotka–Volterra predator–prey system incorporating fear effect
We propose and study a Lotka–Volterra predator–prey system incorporating both Michaelis–Menten-type prey harvesting and fear effect. By qualitative analysis of the eigenvalues of the Jacobian matrix we study t...
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Publisher Correction: The Extended Polydimensional Immunome Characterization (EPIC) web-based reference and discovery tool for cytometry data
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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The Extended Polydimensional Immunome Characterization (EPIC) web-based reference and discovery tool for cytometry data
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Article
Open AccessThe influence of fear effect to the Lotka–Volterra predator–prey system with predator has other food resource
A Lotka–Volterra predator–prey system incorporating fear effect of the prey and the predator has other food resource is proposed and studied in this paper. It is shown that the trivial equilibrium and the pred...
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Article
Open AccessStability and bifurcation analysis in a single-species stage structure system with Michaelis–Menten-type harvesting
In this paper, we prpose a single-species stage structure model with Michaelis–Menten-type harvesting for mature population. We investigate the existence of all possible equilibria of the system and discuss th...
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Article
Open Accessp53 increases MHC class I expression by upregulating the endoplasmic reticulum aminopeptidase ERAP1
The p53 tumour suppressor has an important role in cancer cells. Here we show that p53 regulates expression of major histocompatibility complex I on the cell surface. We show that the tumour cell line HCT116, ...
