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  1. No Access

    Article

    CD14+ HLA-DR−/low MDSCs are elevated in the periphery of early-stage breast cancer patients and suppress autologous T cell proliferation

    Despite the recent expansion in the use of immunotherapy for many cancer types, it is still not a standard treatment for breast cancer. Identifying differences in the immune systems of breast cancer patients c...

    Lisa Speigl, Helen Burow, Jithendra Kini Bailur… in Breast Cancer Research and Treatment (2018)

  2. No Access

    Article

    Peripheral T cell responses to tumour antigens are associated with molecular, immunogenetic and cellular features of breast cancer patients

    Breast cancer is a leading cause of cancer deaths in women, but despite steady improvements in therapies, treatment is still suboptimal. Immunotherapy holds promise as a more effective therapy for breast cance...

    Nicole Janssen, Sotirios P. Fortis, Lisa Speigl… in Breast Cancer Research and Treatment (2017)

  3. No Access

    Article

    A clinical and biological perspective of human myeloid-derived suppressor cells in cancer

    Considering the large number of studies focused on myeloid-derived suppressor cells (MDSCs) to date, only a handful of well-defined relationships in human cancer have been established. The difficulty of assess...

    Christopher Shipp, Lisa Speigl, Nicole Janssen… in Cellular and Molecular Life Sciences (2016)

  4. Article

    Open Access

    Immune profiling of breast cancer patients: relationship between tumour antigen T cell responses with suppressor and effector leukocyte populations

    Nicole Janssen, Graham Pawelec, Lisa Speigl… in Journal for ImmunoTherapy of Cancer (2015)

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