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  1. Article

    Open Access

    In vitro-Amplifikation humaner hämatopoetischer Stammzellen im 3D-System

    A promising strategy to increase the numbers of hematopoietic stem cells (HSCs) for clinical applications, like stem cell transplantation, is offered by advanced in vitro culture systems. We developed artificial ...

    Lisa Marx-Blümel, Christian Marx, Andreas Schober, James F. Beck in BIOspektrum (2022)

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    Article

    The sirtuin 1/2 inhibitor tenovin-1 induces a nonlinear apoptosis-inducing factor-dependent cell death in a p53 null Ewing’s sarcoma cell line

    The sirtuin 1/2 inhibitor tenovin-1 activates p53 and may have potential in the management of cancer. Here, we investigated the responsiveness of Ewing’s sarcoma cells to tenovin-1. We examined its effects in ...

    Christian Marx, Lisa Marx-Blümel, Nora Lindig, René Thierbach in Investigational New Drugs (2018)