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  1. No Access

    Article

    CD22 CAR T cells demonstrate high response rates and safety in pediatric and adult B-ALL: Phase 1b results

    Chimeric antigen receptor (CAR) T cells targeting CD22 (CD22-CAR) provide a therapeutic option for patients with CD22+ malignancies with progression after CD19-directed therapies. Using on-site, automated, closed...

    Liora M. Schultz, Nikeshan Jeyakumar, Anne Marijn Kramer, Bita Sahaf… in Leukemia (2024)

  2. Article

    Open Access

    GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas

    Diffuse intrinsic pontine glioma (DIPG) and other H3K27M-mutated diffuse midline gliomas (DMGs) are universally lethal paediatric tumours of the central nervous system1. We have previously shown that the disialog...

    Robbie G. Majzner, Sneha Ramakrishna, Kristen W. Yeom, Shabnum Patel… in Nature (2022)

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  3. No Access

    Article

    HLA-haplotype loss after TCRαβ/CD19-depleted haploidentical HSCT

    David C. Shyr, Bing M. Zhang, Gopin Saini, Nahid D. Madani… in Bone Marrow Transplantation (2021)