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Article
Children with Congenital Heart Diseases Exhibit Altered Deep Gray Matter Structures
Children with congenital heart diseases (CHDs) have an increased risk of develo** neurologic deficits, even in the absence of apparent brain pathology. The aim of this work was to compare quantitative macro-...
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Article
Increased confidence of radiomics facilitating pretherapeutic differentiation of BRAF-altered pediatric low-grade glioma
Currently, the BRAF status of pediatric low-grade glioma (pLGG) patients is determined through a biopsy. We established a nomogram to predict BRAF status non-invasively using clinical and radiomic factors. Add...
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Article
Open AccessDEEP MOVEMENT: Deep learning of movie files for management of endovascular thrombectomy
Treatment and outcomes of acute stroke have been revolutionised by mechanical thrombectomy. Deep learning has shown great promise in diagnostics but applications in video and interventional radiology lag behin...
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Article
Open AccessCorrection to: Radiology artificial intelligence: a systematic review and evaluation of methods (RAISE)
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Article
Open AccessRadiology artificial intelligence: a systematic review and evaluation of methods (RAISE)
There has been a large amount of research in the field of artificial intelligence (AI) as applied to clinical radiology. However, these studies vary in design and quality and systematic reviews of the entire f...
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Article
Age-dependent Intracranial Artery Morphology in Healthy Children
Evaluation of intracranial artery morphology plays an important role in diagnosing a variety of neurovascular diseases. In addition to clinical symptoms, diagnosis currently relies on qualitative rather than q...
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Article
Open AccessGD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas
Diffuse intrinsic pontine glioma (DIPG) and other H3K27M-mutated diffuse midline gliomas (DMGs) are universally lethal paediatric tumours of the central nervous system1. We have previously shown that the disialog...
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Article
Open AccessAttention-guided deep learning for gestational age prediction using fetal brain MRI
Magnetic resonance imaging offers unrivaled visualization of the fetal brain, forming the basis for establishing age-specific morphologic milestones. However, gauging age-appropriate neural development remains...
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Article
Correction to: End-to-end automatic differentiation of the coronavirus disease 2019 (COVID-19) from viral pneumonia based on chest CT
A Correction to this paper has been published: https://doi.org/10.1007/s00259-021-05267-6
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Article
Correction to: Decoding COVID-19 pneumonia: comparison of deep learning and radiomics CT image signatures
A Correction to this paper has been published: https://doi.org/10.1007/s00259-021-05268-5
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Article
Open AccessDecoding COVID-19 pneumonia: comparison of deep learning and radiomics CT image signatures
High-dimensional image features that underlie COVID-19 pneumonia remain opaque. We aim to compare feature engineering and deep learning methods to gain insights into the image features that drive CT-based for ...
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Article
Simultaneous time of flight-MRA and T2* imaging for cerebrovascular MRI
3D multi-echo gradient-recalled echo (ME-GRE) can simultaneously generate time-of-flight magnetic resonance angiography (pTOF) in addition to T2*-based susceptibility-weighted images (SWI). We assessed the cli...
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Article
Open AccessDeep COVID DeteCT: an international experience on COVID-19 lung detection and prognosis using chest CT
The Coronavirus disease 2019 (COVID-19) presents open questions in how we clinically diagnose and assess disease course. Recently, chest computed tomography (CT) has shown utility for COVID-19 diagnosis. In th...
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Article
Open AccessRadiology artificial intelligence, a systematic evaluation of methods (RAISE): a systematic review protocol
There has been a recent explosion of research into the field of artificial intelligence as applied to clinical radiology with the advent of highly accurate computer vision technology. These studies, however, v...
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Article
Open AccessEnd-to-end automatic differentiation of the coronavirus disease 2019 (COVID-19) from viral pneumonia based on chest CT
In the absence of a virus nucleic acid real-time reverse transcriptase-polymerase chain reaction (RT-PCR) test and experienced radiologists, clinical diagnosis is challenging for viral pneumonia with clinical ...
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Article
Children with epilepsy demonstrate macro- and microstructural changes in the thalamus, putamen, and amygdala
Despite evidence for macrostructural alteration in epilepsy patients later in life, little is known about the underlying pathological or compensatory mechanisms at younger ages causing these alterations. The a...
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Article
Open AccessPublisher Correction: Development of an optogenetic toolkit for neural circuit dissection in squirrel monkeys
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Age-Dependent White Matter Characteristics of the Cerebellar Peduncles from Infancy Through Adolescence
Cerebellum-cerebrum connections are essential for many motor and cognitive functions and cerebellar disorders are prevalent in childhood. The middle (MCP), inferior (ICP), and superior cerebellar peduncles (SC...
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Article
Open AccessDevelopment of an optogenetic toolkit for neural circuit dissection in squirrel monkeys
Optogenetic tools have opened a rich experimental landscape for understanding neural function and disease. Here, we present the first validation of eight optogenetic constructs driven by recombinant adeno-asso...
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Article
Chemoradiation impairs normal developmental cortical thinning in medulloblastoma
Medulloblastoma patients are treated with surgery, radiation and chemotherapy. Radiation dose to the temporal lobe may be associated with neurocognitive sequelae. Longitudinal changes of temporal lobe cortical...