Skip to main content

3 Result(s)

within Linqing Miao Remove this filter

and

  1. Article

    Open Access

    AKT-dependent and -independent pathways mediate PTEN deletion-induced CNS axon regeneration

    Phosphatase and tensin homolog (PTEN) acts as a brake for the phosphatidylinositol 3-kinase–AKT–mTOR complex 1 (mTORC1) pathway, the deletion of which promotes potent central nervous system (CNS) axon regenera...

    Haoliang Huang, Linqing Miao, Liu Yang, Feisi Liang, Qizhao Wang… in Cell Death & Disease (2019)

    Download PDF (6420 KB) View Article

  2. Article

    Open Access

    Neuroprotection by eIF2α-CHOP inhibition and XBP-1 activation in EAE/optic neuritiss

    No therapies exist to prevent neuronal deficits in multiple sclerosis (MS), because the molecular mechanism responsible for the progressive neurodegeneration is unknown. We previously showed that axon injury-i...

    Haoliang Huang, Linqing Miao, Feisi Liang, **aodong Liu, Lin Xu… in Cell Death & Disease (2017)

    Download PDF (5456 KB) View Article

  3. No Access

    Article

    The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration

    Using mouse optic nerve (ON) crush as a CNS injury model, we and others have found that activation of the mammalian target of rapamycin complex 1 (mTORC1) in mature retinal ganglion cells by deletion of the ne...

    Liu Yang, Linqing Miao, Feisi Liang, Haoliang Huang, **uyin Teng… in Nature Communications (2014)