12 Result(s)
within
Lindsay M. Squeglia
Neurosciences
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Article
N-acetylcysteine does not alter neurometabolite levels in non-treatment seeking adolescents who use alcohol heavily: A preliminary randomized clinical trial
Current treatments for adolescent alcohol use disorder (AUD) are mainly psychosocial and limited in their efficacy. As such, pharmacotherapies are being investigated as potential adjunctive treatments to bolst...
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Brain metabolite alterations related to alcohol use: a meta-analysis of proton magnetic resonance spectroscopy studies
Alcohol misuse and alcohol use disorder (AlUD) have neurobiological consequences. This meta-analysis of proton magnetic resonance spectroscopy (MRS) studies aimed to assess the differences in brain metabolite ...
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Neural vulnerability and hurricane-related media are associated with post-traumatic stress in youth
The human toll of disasters extends beyond death, injury and loss. Post-traumatic stress (PTS) can be common among directly exposed individuals, and children are particularly vulnerable. Even children far remo...
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Depressive symptoms and cannabis use in a placebo-controlled trial of N-Acetylcysteine for adult cannabis use disorder
Depression is common among individuals with cannabis use disorder (CUD), particularly individuals who present to CUD treatment. Treatments that consider this comorbidity are essential.
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Neurobiological and Cognitive Profile of Young Binge Drinkers: a Systematic Review and Meta-Analysis
This review provides the first systematic and quantitative synthesis of the literature examining the relationship between binge drinking, cognition, brain structure and function in youth aged 10 to 24 years. P...
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Prospective changes in neural alcohol cue reactivity in at-risk adolescents
Adolescence represents an ideal time for elucidating the etiology of cue reactivity profiles. This study examined the influence of three risk factors consistently associated with heavy adolescent drinking on a...
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Earlier alcohol use onset prospectively predicts changes in functional connectivity
Half of all new alcohol initiates are between 12 and 17 years old. This is a period of intense neurodevelopment, including changes in functional connectivity patterns among higher-order function areas. It is c...
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Changes in marijuana use symptoms and emotional functioning over 28-days of monitored abstinence in adolescent marijuana users
Advancing marijuana prevention and intervention efforts are important given the decreasing perception of harm among adolescents and increasing marijuana legalization.
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Alcohol consumption as a predictor of reactivity to smoking and stress cues presented in the natural environment of smokers
The high prevalence of co-occurring alcohol and tobacco use underscores the importance of understanding the influence of alcohol consumption on risk factors for smoking and relapse. Alcohol has been shown to i...
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Article
Structural connectivity of neural reward networks in youth at risk for substance use disorders
Having a positive family history of alcohol use disorders (FHP), as well as aberrant reward circuitry, has been implicated in the initiation of substance use during adolescence. This study explored the relatio...
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A longitudinal examination of adolescent response inhibition: neural differences before and after the initiation of heavy drinking
Response inhibition abnormalities contribute to several maladaptive behaviors commonly observed during adolescence, including heavy drinking.
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Binge drinking differentially affects adolescent male and female brain morphometry
Adolescent binge drinking is concerning, as important neurodevelopments occur during this stage. Previous research suggests that binge drinking may disrupt typical brain development, and females may be particu...
