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  1. Article

    Open Access

    QL1706 (anti-PD-1 IgG4/CTLA-4 antibody) plus chemotherapy with or without bevacizumab in advanced non-small cell lung cancer: a multi-cohort, phase II study

    First-line chemoimmunotherapy (with or without bevacizumab) has improved outcomes in advanced non-small cell lung cancer (NSCLC). Here, this open-label, multi-cohort phase II study (NCT05329025) was done to in...

    Yan Huang, Yunpeng Yang, Yuanyuan Zhao in Signal Transduction and Targeted Therapy (2024)

  2. Article

    Open Access

    Retraction Note: N6-methyladenosine induced mir-143-3p promotes the brain metastasis of lung cancer via regulation of VASH1

    Hongsheng Wang, Qianqian Deng, Ziyan Lv, Yuyi Ling, Xue Hou in Molecular Cancer (2023)

  3. No Access

    Article

    A dielectric electrolyte composite with high lithium-ion conductivity for high-voltage solid-state lithium metal batteries

    The ionic conductivity of composite solid-state electrolytes does not meet the application requirements of solid-state lithium (Li) metal batteries owing to the harsh space charge layer of different phases and...

    Peiran Shi, Jiabin Ma, Ming Liu, Shaoke Guo, Yanfei Huang in Nature Nanotechnology (2023)

  4. Article

    Open Access

    Retraction Note: p300 promotes proliferation, migration, and invasion via inducing epithelial-mesenchymal transition in non-small cell lung cancer cells

    This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12885-018-4559-3.

    Xue Hou, Run Gong, Jianhua Zhan, Ting Zhou, Yuxiang Ma, Yuanyuan Zhao in BMC Cancer (2023)

  5. Article

    Open Access

    Correction: Dynamic monitoring of cerebrospinal fluid circulating tumor DNA to identify unique genetic profiles of brain metastatic tumors and better predict intracranial tumor responses in non-small cell lung cancer patients with brain metastases: a prospective cohort study (GASTO 1028)

    Meichen Li, **g Chen, Baishen Zhang, Juan Yu, Na Wang, Delan Li, Yang Shao in BMC Medicine (2023)

  6. Article

    Open Access

    Dynamic monitoring of cerebrospinal fluid circulating tumor DNA to identify unique genetic profiles of brain metastatic tumors and better predict intracranial tumor responses in non-small cell lung cancer patients with brain metastases: a prospective cohort study (GASTO 1028)

    Due to the blood-brain barrier, plasma is not an ideal source to evaluate the genetic characteristics of central nervous system tumors. Thus, cerebrospinal fluid (CSF) is becoming an alternative biopsy type to...

    Meichen Li, **g Chen, Baishen Zhang, Juan Yu, Na Wang, Delan Li, Yang Shao in BMC Medicine (2022)

  7. No Access

    Chapter and Conference Paper

    Islanding and Grid Disturbance Detection Based on Multi-SVMs Delay Validation in Synchronous Dominated Microgrids

    Intrinsically active, passive, or a hybrid method of the two is the main methods for solving the problem of islanding detection in microgrids. For islanding and disturbance detection, most methods rely on the ...

    Dan Zhou, Meiling Deng, Xu Deng in Advances in Artificial Systems for Power E… (2022)

  8. No Access

    Article

    Impact of STAT1 polymorphisms on crizotinib-induced hepatotoxicity in ALK-positive non-small cell lung cancer patients

    Crizotinib is the first-line small molecule tyrosine kinase inhibitor for ALK-positive non-small cell lung cancer. In this study, a retrospective pharmacogenomics investigation was conducted to explore the relati...

    Shuang **n, Wenfeng Fang, Jianwen Li in Journal of Cancer Research and Clinical On… (2021)

  9. No Access

    Article

    Genomic origin and intratumor heterogeneity revealed by sequencing on carcinomatous and sarcomatous components of pulmonary sarcomatoid carcinoma

    Pulmonary sarcomatoid carcinoma (PSC) contains carcinomatous component (CaC) and sarcomatous component (SaC). Herein, we explored the genomic origin and intratumor heterogeneity (ITH) of PSC. We collected 31 r...

    Xuewen Liu, Fang Wang, Chunwei Xu, **nru Chen, Xue Hou, Qian Li, Pansong Li in Oncogene (2021)

  10. Article

    Open Access

    Author Correction: ABCG2-overexpressing H460/MX20 cell xenografts in athymic nude mice maintained original biochemical and cytological characteristics

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Wei Zhang, Zhen Chen, Likun Chen, Fang Wang, Furong Li, **aokun Wang in Scientific Reports (2020)

  11. Article

    Open Access

    Correction: Alectinib (CH5424802) antagonizes ABCB1- and ABCG2-mediated multidrug resistance in vitro, in vivo and ex vivo

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Ke Yang, Yifan Chen, Kenneth Kin Wah To, Fang Wang in Experimental & Molecular Medicine (2020)

  12. Article

    Erratum to: Decontamination of Chemical Warfare Agents by Novel Oximated Acrylate Copolymer

    The original version of this article unfortunately con-tained a mistake. The presentation of corresponding authors was incorrect. The corrected corresponding authors labeled with asterisk are given below.

    **anfang Wen, Lin Ye, Likun Chen, Lingce Kong in Chemical Research in Chinese Universities (2020)

  13. Article

    Erratum to: Decontamination of Chemical Warfare Agents by Novel Oximated Acrylate Copolymer

    The original version of this article unfortunately con-tained a mistake. The presentation of corresponding authors was incorrect. The corrected corresponding authors labeled with asterisk are given below.

    **anfang Wen, Lin Ye, Likun Chen, Lingce Kong in Chemical Research in Chinese Universities (2020)

  14. Article

    Open Access

    Reversal of ABCB1-related multidrug resistance by ERK5-IN-1

    Inhibition of ABC transporters is considered the most effective way to circumvent multidrug resistance (MDR). In the present study, we evaluated the MDR modulatory potential of ERK5-IN-1, a potent extracelluar...

    Fang Wang, Delan Li, ZongHeng Zheng in Journal of Experimental & Clinical Cancer … (2020)

  15. Article

    Open Access

    Chemotherapeutic drugs stimulate the release and recycling of extracellular vesicles to assist cancer cells in develo** an urgent chemoresistance

    Chemotherapy is a widely used treatment for cancer. However, the development of acquired multidrug resistance (MDR) is a serious issue. Emerging evidence has shown that the extracellular vesicles (EVs) mediate...

    **aokun Wang, Dongjuan Qiao, Likun Chen, Meng Xu, Shupeng Chen in Molecular Cancer (2019)

  16. Article

    Open Access

    RETRACTED ARTICLE: N6-methyladenosine induced miR-143-3p promotes the brain metastasis of lung cancer via regulation of VASH1

    Brain metastasis (BM) is one of the principal causes of mortality for lung cancer patients. While the molecular events that govern BM of lung cancer remain frustrating cloudy.

    Hongsheng Wang, Qianqian Deng, Ziyan Lv, Yuyi Ling, Xue Hou in Molecular Cancer (2019)

  17. No Access

    Article

    Decontamination of Chemical Warfare Agents by Novel Oximated Acrylate Copolymer

    A novel acrylate copolymer, polymethylacrylate-β-(bromoacetyl ethyl)ester-co-N,N-dimethylacrylamide [P(MABE-co-DMAA)] was synthesized by the copolymerization of N,N-dimethylacrylamide and methylacrylate-β-(bromoa...

    **anfang Wen, Lin Ye, Likun Chen, Lingce Kong in Chemical Research in Chinese Universities (2019)

  18. No Access

    Article

    Targeting CDK7 increases the stability of Snail to promote the dissemination of colorectal cancer

    Targeted inhibition of cyclin-dependent kinase 7 (CDK7) via its covalent inhibitor THZ1 can suppress the growth of various cancers, while its roles on colorectal cancer (CRC) remain obscure. Here we report tha...

    Yan Zhou, Linlin Lu, Guanmin Jiang, Zhuojia Chen, Jiexin Li in Cell Death & Differentiation (2019)

  19. Article

    Open Access

    GALC mutations in Chinese patients with late-onset Krabbe disease: a case report

    Krabbe disease (also known as globoid cell leukodystrophy) cause by a deficiency of the enzyme β-galactocerebrosidase (galactosylceramidase, GALC). The deficiency of GALC leads to accumulation of galactosylcer...

    Shunzhi Zhuang, Lingen Kong, Caiming Li, Likun Chen, Tingting Zhang in BMC Neurology (2019)

  20. Article

    Open Access

    RETRACTED ARTICLE: p300 promotes proliferation, migration, and invasion via inducing epithelial-mesenchymal transition in non-small cell lung cancer cells

    Histone acetyltransferase p300 is a crucial transcriptional coactivator and has been implicated as a poor prognostic factor in human cancers. However, little is known about the substantial functions and mechan...

    Xue Hou, Run Gong, Jianhua Zhan, Ting Zhou, Yuxiang Ma, Yuanyuan Zhao in BMC Cancer (2018)

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