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Article
Open AccessQL1706 (anti-PD-1 IgG4/CTLA-4 antibody) plus chemotherapy with or without bevacizumab in advanced non-small cell lung cancer: a multi-cohort, phase II study
First-line chemoimmunotherapy (with or without bevacizumab) has improved outcomes in advanced non-small cell lung cancer (NSCLC). Here, this open-label, multi-cohort phase II study (NCT05329025) was done to in...
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Article
Open AccessRetraction Note: N6-methyladenosine induced mir-143-3p promotes the brain metastasis of lung cancer via regulation of VASH1
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Article
A dielectric electrolyte composite with high lithium-ion conductivity for high-voltage solid-state lithium metal batteries
The ionic conductivity of composite solid-state electrolytes does not meet the application requirements of solid-state lithium (Li) metal batteries owing to the harsh space charge layer of different phases and...
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Article
Open AccessRetraction Note: p300 promotes proliferation, migration, and invasion via inducing epithelial-mesenchymal transition in non-small cell lung cancer cells
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12885-018-4559-3.
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Article
Open AccessCorrection: Dynamic monitoring of cerebrospinal fluid circulating tumor DNA to identify unique genetic profiles of brain metastatic tumors and better predict intracranial tumor responses in non-small cell lung cancer patients with brain metastases: a prospective cohort study (GASTO 1028)
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Article
Open AccessDynamic monitoring of cerebrospinal fluid circulating tumor DNA to identify unique genetic profiles of brain metastatic tumors and better predict intracranial tumor responses in non-small cell lung cancer patients with brain metastases: a prospective cohort study (GASTO 1028)
Due to the blood-brain barrier, plasma is not an ideal source to evaluate the genetic characteristics of central nervous system tumors. Thus, cerebrospinal fluid (CSF) is becoming an alternative biopsy type to...
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Chapter and Conference Paper
Islanding and Grid Disturbance Detection Based on Multi-SVMs Delay Validation in Synchronous Dominated Microgrids
Intrinsically active, passive, or a hybrid method of the two is the main methods for solving the problem of islanding detection in microgrids. For islanding and disturbance detection, most methods rely on the ...
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Article
Impact of STAT1 polymorphisms on crizotinib-induced hepatotoxicity in ALK-positive non-small cell lung cancer patients
Crizotinib is the first-line small molecule tyrosine kinase inhibitor for ALK-positive non-small cell lung cancer. In this study, a retrospective pharmacogenomics investigation was conducted to explore the relati...
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Article
Genomic origin and intratumor heterogeneity revealed by sequencing on carcinomatous and sarcomatous components of pulmonary sarcomatoid carcinoma
Pulmonary sarcomatoid carcinoma (PSC) contains carcinomatous component (CaC) and sarcomatous component (SaC). Herein, we explored the genomic origin and intratumor heterogeneity (ITH) of PSC. We collected 31 r...
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Article
Open AccessAuthor Correction: ABCG2-overexpressing H460/MX20 cell xenografts in athymic nude mice maintained original biochemical and cytological characteristics
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessCorrection: Alectinib (CH5424802) antagonizes ABCB1- and ABCG2-mediated multidrug resistance in vitro, in vivo and ex vivo
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Erratum to: Decontamination of Chemical Warfare Agents by Novel Oximated Acrylate Copolymer
The original version of this article unfortunately con-tained a mistake. The presentation of corresponding authors was incorrect. The corrected corresponding authors labeled with asterisk are given below.
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Article
Erratum to: Decontamination of Chemical Warfare Agents by Novel Oximated Acrylate Copolymer
The original version of this article unfortunately con-tained a mistake. The presentation of corresponding authors was incorrect. The corrected corresponding authors labeled with asterisk are given below.
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Article
Open AccessReversal of ABCB1-related multidrug resistance by ERK5-IN-1
Inhibition of ABC transporters is considered the most effective way to circumvent multidrug resistance (MDR). In the present study, we evaluated the MDR modulatory potential of ERK5-IN-1, a potent extracelluar...
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Article
Open AccessChemotherapeutic drugs stimulate the release and recycling of extracellular vesicles to assist cancer cells in develo** an urgent chemoresistance
Chemotherapy is a widely used treatment for cancer. However, the development of acquired multidrug resistance (MDR) is a serious issue. Emerging evidence has shown that the extracellular vesicles (EVs) mediate...
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Article
Open AccessRETRACTED ARTICLE: N6-methyladenosine induced miR-143-3p promotes the brain metastasis of lung cancer via regulation of VASH1
Brain metastasis (BM) is one of the principal causes of mortality for lung cancer patients. While the molecular events that govern BM of lung cancer remain frustrating cloudy.
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Article
Decontamination of Chemical Warfare Agents by Novel Oximated Acrylate Copolymer
A novel acrylate copolymer, polymethylacrylate-β-(bromoacetyl ethyl)ester-co-N,N-dimethylacrylamide [P(MABE-co-DMAA)] was synthesized by the copolymerization of N,N-dimethylacrylamide and methylacrylate-β-(bromoa...
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Article
Targeting CDK7 increases the stability of Snail to promote the dissemination of colorectal cancer
Targeted inhibition of cyclin-dependent kinase 7 (CDK7) via its covalent inhibitor THZ1 can suppress the growth of various cancers, while its roles on colorectal cancer (CRC) remain obscure. Here we report tha...
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Article
Open AccessGALC mutations in Chinese patients with late-onset Krabbe disease: a case report
Krabbe disease (also known as globoid cell leukodystrophy) cause by a deficiency of the enzyme β-galactocerebrosidase (galactosylceramidase, GALC). The deficiency of GALC leads to accumulation of galactosylcer...
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Article
Open AccessRETRACTED ARTICLE: p300 promotes proliferation, migration, and invasion via inducing epithelial-mesenchymal transition in non-small cell lung cancer cells
Histone acetyltransferase p300 is a crucial transcriptional coactivator and has been implicated as a poor prognostic factor in human cancers. However, little is known about the substantial functions and mechan...