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  1. Article

    Open Access

    Signaling mechanisms in renal compensatory hypertrophy revealed by multi-omics

    Loss of a kidney results in compensatory growth of the remaining kidney, a phenomenon of considerable clinical importance. However, the mechanisms involved are largely unknown. Here, we use a multi-omic approa...

    Hiroaki Kikuchi, Chung-Lin Chou, Chin-Rang Yang, Lihe Chen in Nature Communications (2023)

  2. Article

    Open Access

    NGS-Integrator: An efficient tool for combining multiple NGS data tracks using minimum Bayes’ factors

    Next-generation sequencing (NGS) is widely used for genome-wide identification and quantification of DNA elements involved in the regulation of gene transcription. Studies that generate multiple high-throughpu...

    Bronte Wen, Hyun Jun Jung, Lihe Chen, Fahad Saeed, Mark A. Knepper in BMC Genomics (2020)

  3. Chapter

    Erratum to: Development and Diseases of the Collecting Duct System

    Lihe Chen, Paul J. Higgins, Wenzheng Zhang in Kidney Development and Disease (2017)

  4. No Access

    Chapter

    Development and Diseases of the Collecting Duct System

    The collecting duct of the mammalian kidney is important for the regulation of extracellular volume, osmolarity, and pH. There are two major structurally and functionally distinct cell types: principal cells a...

    Lihe Chen, Paul J. Higgins, Wenzheng Zhang in Kidney Development and Disease (2017)