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Article
Open AccessSignaling mechanisms in renal compensatory hypertrophy revealed by multi-omics
Loss of a kidney results in compensatory growth of the remaining kidney, a phenomenon of considerable clinical importance. However, the mechanisms involved are largely unknown. Here, we use a multi-omic approa...
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Article
Open AccessBayesian analysis of dynamic phosphoproteomic data identifies protein kinases mediating GPCR responses
A major goal in the discovery of cellular signaling networks is to identify regulated phosphorylation sites (“phosphosites”) and map them to the responsible protein kinases. The V2 vasopressin receptor is a G-...
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Chapter
Regulation of Renal Aquaporins and Sodium Transporters During Vasopressin-Escape in the Rat
Several clinical conditions, e.g., congestive heart failure and cirrhosis are associated with inappropriately elevated vasopressin levels relative to serum osmolality (Bichet et al., 1992). In addition, ectopic p...
