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Open AccessManagement of intra-abdominal infections: recommendations by the Italian council for the optimization of antimicrobial use
Intra-abdominal infections (IAIs) are common surgical emergencies and are an important cause of morbidity and mortality in hospital settings, particularly if poorly managed. The cornerstones of effective IAIs ...
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Article
Open AccessContinuous assessment of neuro-ventilatory drive during 12 h of pressure support ventilation in critically ill patients
Pressure support ventilation (PSV) should allow spontaneous breathing with a “normal” neuro-ventilatory drive. Low neuro-ventilatory drive puts the patient at risk of diaphragmatic atrophy while high neuro-ven...
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Article
Open AccessHemodynamic goal-directed therapy and postoperative kidney injury: an updated meta-analysis with trial sequential analysis
Perioperative goal-directed therapy (GDT) reduces the risk of renal injury. However, several questions remain unanswered, such as target, kind of patients and surgery, and role of fluids and inotropes. We ther...
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Article
Open AccessCost of care and antibiotic prescribing attitudes for community-acquired complicated intra-abdominal infections in Italy: a retrospective study
Complicated intra-abdominal infections (cIAIs) are a common cause of morbidity worldwide, and in spite of improvements in patient care, therapeutic failure still occurs, impacting in-hospital resource consumpt...
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Article
Open AccessOral nystatin prophylaxis in surgical/trauma ICU patients: a randomised clinical trial
Candida prophylaxis in ICU is still a matter of debate. Oral chemoprophylaxis has been advocated to reduce the incidence of Candida colonisation and infection.
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Article
Open AccessHaemodynamic goal-directed therapy and postoperative infections: earlier is better. a systematic review and meta-analysis
Infectious complications are the main causes of postoperative morbidity. The early timing of their promoting factors is the rationale for perioperative strategies attempting to reduce them. Our aim was to dete...