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Article
Open AccessContinuous assessment of neuro-ventilatory drive during 12 h of pressure support ventilation in critically ill patients
Pressure support ventilation (PSV) should allow spontaneous breathing with a “normal” neuro-ventilatory drive. Low neuro-ventilatory drive puts the patient at risk of diaphragmatic atrophy while high neuro-ven...
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Article
Open AccessHemodynamic goal-directed therapy and postoperative kidney injury: an updated meta-analysis with trial sequential analysis
Perioperative goal-directed therapy (GDT) reduces the risk of renal injury. However, several questions remain unanswered, such as target, kind of patients and surgery, and role of fluids and inotropes. We ther...
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Article
Open AccessOral nystatin prophylaxis in surgical/trauma ICU patients: a randomised clinical trial
Candida prophylaxis in ICU is still a matter of debate. Oral chemoprophylaxis has been advocated to reduce the incidence of Candida colonisation and infection.
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Article
Open AccessHaemodynamic goal-directed therapy and postoperative infections: earlier is better. a systematic review and meta-analysis
Infectious complications are the main causes of postoperative morbidity. The early timing of their promoting factors is the rationale for perioperative strategies attempting to reduce them. Our aim was to dete...
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Article
Intra-abdominal hypertensionand acute renal failurein critically ill patients
To investigate the relationship between intra-abdominal hypertension (IAH) and acute renal failure (ARF) in critically ill patients.
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Article
Jaundice in critical illness: promoting factors of a concealed reality
In critical illness, liver dysfunction (LD) is associated with a poor outcome independently of other organ dysfunctions. Since strategies to support liver function are not available, a timely and accurate iden...