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Open AccessCharacteristics of blood immune cell profile and their correlation with disease progression in patients infected with HIV-1
Antiretroviral therapy (ART) can reduce viral load in individuals infected with human immunodeficiency virus (HIV); however, some HIV-infected individuals still cannot achieve optimal immune recovery even afte...
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Article
Identification and analysis of B cell epitopes of hemagglutinin of H1N1 influenza virus
The frequent variation of influenza virus hemagglutinin (HA) antigen is the main cause of influenza pandemic. Therefore, the study of B cell epitopes of HA is of great significance in the prevention and contro...
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Monoclonal Antibody Targeting the HA191/199 Region of H1N1 Influenza Virus Mediates the Damage of Neural Cells
Vaccination is the most effective mean of preventing influenza virus infections. However, vaccination-induced adverse reactions of the nervous system, the causes of which are unknown, lead to concerns on the s...
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Open AccessTwo kinds of rare light chain cast nephropathy caused by multiple myeloma: case reports and literature review
Light chain cast nephropathy (LCCN) is the most common renal disease caused by multiple myeloma (MM). In addition to ordinary light chain protein casts, there are a few rare casts with unique shapes, including...
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Open AccessSMRT sequencing revealed to be an effective method for ADTKD-MUC1 diagnosis through follow-up analysis of a Chinese family
We reported a large Chinese family diagnosed with autosomal dominant tubulointerstitial kidney disease caused by MUC1 mutation (ADTKD-MUC1). Cytosine duplication within a string of 7 cytosines in the variable-num...
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Clinical characteristics of 34 COVID-19 patients admitted to intensive care unit in Hangzhou, China
This study summarizes and compares clinical and laboratory characteristics of 34 patients admitted to the intensive care unit (ICU) for complications from coronavirus disease 2019 (COVID-19) at the First Affil...
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Localization Analysis of Heterophilic Antigen Epitopes of H1N1 Influenza Virus Hemagglutinin
Previous studies have indicated that two monoclonal antibodies (mAbs; A1-10 and H1-84) of the hemagglutinin (HA) antigen on the H1N1 influenza virus cross-react with human brain tissue. It has been proposed th...
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Open AccessHuman papillomavirus-related psychosocial impact of patients with genital warts in China: a hospital-based cross-sectional study
Genital warts (GW) are the most common sexually transmitted infections. To date, few studies using a human papillomavirus (HPV)-specific questionnaire have focused on the impact of quality of life (QoL) among ...
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Open AccessImpact of genital warts on health related quality of life in men and women in mainland China: a multicenter hospital-based cross-sectional study
Information on the health-related quality of life (HRQoL) of patients with genital warts (GW) in populations in mainland China is still limited. The aim of the study was to use a generic instrument to measure ...
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RETRACTED ARTICLE: Cytotoxic activities of tubeimoside-2 on human hepatoma HepG2 cells by induction of G2/M phase arrest and apoptosis in a p53-dependent manner