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  1. Article

    Open Access

    FZD5 prevents epithelial-mesenchymal transition in gastric cancer

    Frizzled (FZD) proteins function as receptors for WNT ligands. Members in FZD family including FZD2, FZD4, FZD7, FZD8 and FZD10 have been demonstrated to mediate cancer cell epithelial-mesenchymal transition (...

    Dan Dong, Lei Na, Kailing Zhou, Zhuo Wang, Yu Sun… in Cell Communication and Signaling (2021)

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  2. Article

    Open Access

    FZD5 contributes to TNBC proliferation, DNA damage repair and stemness

    Chemotherapy currently remains the standard treatment for triple-negative breast cancer (TNBC). However, TNBC frequently develop chemoresistance, which is responsible for cancer recurrence and distal metastasi...

    Yu Sun, Zhuo Wang, Lei Na, Dan Dong, Wei Wang, Chenghai Zhao in Cell Death & Disease (2020)

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  3. Article

    Open Access

    Non-canonical Fzd7 signaling contributes to breast cancer mesenchymal-like stemness involving Col6a1

    Mesenchymal-like stemness is characterized by epithelial-mesenchymal transition (EMT). Breast cancer (BC) cell mesenchymal-like stemness is responsible for distal lung metastasis. Interrogation of databases sh...

    ** Yin, Yu Bai, Zhuo Wang, Yu Sun, Jian Gao, Lei Na… in Cell Communication and Signaling (2020)

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  4. No Access

    Article

    The TRIMCyp genotype in four species of macaques in China

    The tripartite motif protein (TRIM)5α/CypA fusion protein TRIMCyp in Old World monkeys is generally considered unable to restrict HIV-1 replication. Monkeys with TRIMCyp can serve as a unique animal model for ...

    Chang-Qing Yu, Lei Na, **ao-Ling Lv, Jian-Dong Liu, **ao-Ming Liu… in Immunogenetics (2013)