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  1. Article

    Open Access

    Harbinger transposon insertion in ethylene signaling gene leads to emergence of new sexual forms in cucurbits

    In flowering plants, the predominant sexual morph is hermaphroditism, and the emergence of unisexuality is poorly understood. Using Cucumis melo (melon) as a model system, we explore the mechanisms driving sexual...

    Hsin-Ya Huang, Siqi Zhang, Fadi Abou Choucha, Marion Verdenaud in Nature Communications (2024)

  2. Article

    Open Access

    The Arabidopsis APOLO and human UPAT sequence-unrelated long noncoding RNAs can modulate DNA and histone methylation machineries in plants

    RNA-DNA hybrid (R-loop)-associated long noncoding RNAs (lncRNAs), including the Arabidopsis lncRNA AUXIN-REGULATED PROMOTER LOOP (APOLO), are emerging as important regulators of three-dimensional chromatin confor...

    Camille Fonouni-Farde, Aurélie Christ, Thomas Blein in Genome Biology (2022)

  3. Article

    Open Access

    Author Correction: The impact of transposable elements on tomato diversity

    Marisol Domínguez, Elise Dugas, Médine Benchouaia, Basile Leduque in Nature Communications (2021)

  4. Article

    Open Access

    Genetic and environmental modulation of transposition shapes the evolutionary potential of Arabidopsis thaliana

    How species can adapt to abrupt environmental changes, particularly in the absence of standing genetic variation, is poorly understood and a pressing question in the face of ongoing climate change. Here we lev...

    Pierre Baduel, Basile Leduque, Amandine Ignace, Isabelle Gy, José Gil Jr in Genome Biology (2021)

  5. No Access

    Protocol

    Detection of Transposable Element Insertions in Arabidopsis Using Sequence Capture

    Transposable elements (TEs) are repetitive DNA sequences that have the ability to mobilize in the genome and create major effect mutations. Despite the importance of transposition as a source of genetic novelt...

    Leandro Quadrana, Amanda Bortolini Silveira in Plant Transposable Elements (2021)

  6. No Access

    Protocol

    Efficient Detection of Transposable Element Insertion Polymorphisms Between Genomes Using Short-Read Sequencing Data

    Transposable elements (TEs) are powerful generators of major-effect mutations, most of which are deleterious at the species level and maintained at very low frequencies within populations. As reference genomes...

    Pierre Baduel, Leandro Quadrana, Vincent Colot in Plant Transposable Elements (2021)

  7. Article

    Open Access

    The impact of transposable elements on tomato diversity

    Tomatoes come in a multitude of shapes and flavors despite a narrow genetic pool. Here, we leverage whole-genome resequencing data available for 602 cultivated and wild accessions to determine the contribution...

    Marisol Domínguez, Elise Dugas, Médine Benchouaia, Basile Leduque in Nature Communications (2020)

  8. Article

    Open Access

    Relaxed purifying selection in autopolyploids drives transposable element over-accumulation which provides variants for local adaptation

    Polyploidization is frequently associated with increased transposable element (TE) content. However, what drives TE dynamics following whole genome duplication (WGD) and the evolutionary implications remain un...

    Pierre Baduel, Leandro Quadrana, Ben Hunter, Kirsten Bomblies in Nature Communications (2019)

  9. Article

    Open Access

    Transposition favors the generation of large effect mutations that may facilitate rapid adaption

    Transposable elements (TEs) are mobile parasitic sequences that have been repeatedly coopted during evolution to generate new functions and rewire gene regulatory networks. Yet, the contribution of active TEs ...

    Leandro Quadrana, Mathilde Etcheverry, Arthur Gilly in Nature Communications (2019)

  10. Article

    Open Access

    Differential retention of transposable element-derived sequences in outcrossing Arabidopsis genomes

    Transposable elements (TEs) are genomic parasites with major impacts on host genome architecture and host adaptation. A proper evaluation of their evolutionary significance has been hampered by the paucity of ...

    Sylvain Legrand, Thibault Caron, Florian Maumus, Sol Schvartzman in Mobile DNA (2019)

  11. Article

    Open Access

    TE-Tracker: systematic identification of transposition events through whole-genome resequencing

    Transposable elements (TEs) are DNA sequences that are able to move from their location in the genome by cutting or copying themselves to another locus. As such, they are increasingly recognized as impacting a...

    Arthur Gilly, Mathilde Etcheverry, Mohammed-Amin Madoui, Julie Guy in BMC Bioinformatics (2014)

  12. No Access

    Article

    Natural occurring epialleles determine vitamin E accumulation in tomato fruits

    Vitamin E (VTE) content is a low heritability nutritional trait for which the genetic determinants are poorly understood. Here, we focus on a previously detected major tomato VTE quantitative trait loci (QTL; ...

    Leandro Quadrana, Juliana Almeida, Ramon Asís, Tomás Duffy in Nature Communications (2014)

  13. No Access

    Article

    Transcriptional regulation of tocopherol biosynthesis in tomato

    Tocopherols, compounds with vitamin E (VTE) activity, are potent lipid-soluble antioxidants synthesized only by photosynthetic organisms. Their biosynthesis requires the condensation of phytyl-diphosphate and ...

    Leandro Quadrana, Juliana Almeida, Santiago N. Otaiza in Plant Molecular Biology (2013)

  14. No Access

    Article

    Concerted regulation of nuclear and cytoplasmic activities of SR proteins by AKT

    Serine/arginine-rich (SR) proteins are important regulators of mRNA splicing. Several postsplicing activities have been described for a subset of shuttling SR proteins, including regulation of mRNA export and ...

    Matías Blaustein, Federico Pelisch, Tamara Tanos in Nature Structural & Molecular Biology (2005)