5 Result(s)
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Amanda Bortolini Silveira
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Article
Microsatellite instability detection in breast cancer using drop-off droplet digital PCR
The use of conventional methods (immunohistochemistry, pentaplex PCR) for detecting microsatellite instability (MSI), a predictive biomarker of immunotherapy efficacy, is debated for cancers with low MSI preva...
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Article
Open AccessMultimodal liquid biopsy for early monitoring and outcome prediction of chemotherapy in metastatic breast cancer
Circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) are two cancer-derived blood biomarkers that inform on patient prognosis and treatment efficacy in breast cancer. We prospectively evaluated the...
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Protocol
Detection of Transposable Element Insertions in Arabidopsis Using Sequence Capture
Transposable elements (TEs) are repetitive DNA sequences that have the ability to mobilize in the genome and create major effect mutations. Despite the importance of transposition as a source of genetic novelt...
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Article
Open AccessTransposition favors the generation of large effect mutations that may facilitate rapid adaption
Transposable elements (TEs) are mobile parasitic sequences that have been repeatedly coopted during evolution to generate new functions and rewire gene regulatory networks. Yet, the contribution of active TEs ...
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Article
Epigenetic diversity increases the productivity and stability of plant populations
Biological diversity within species can be an important driver of population and ecosystem functioning. Until now, such within-species diversity effects have been attributed to underlying variation in DNA sequ...
