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  1. No Access

    Article

    Drugs Targeting Cough Receptors: New Therapeutic Options in Refractory or Unexplained Chronic Cough

    Refractory chronic cough is a disabling disease with very limited therapeutic options. A better understanding of cough pathophysiology has led to the development of emerging drugs targeting cough receptors. Re...

    Laurent Guilleminault, Stanislas Grassin-Delyle, Stuart B. Mazzone in Drugs (2024)

  2. Article

    Efficacy and Safety of Eliapixant in Refractory Chronic Cough: The Randomized, Placebo-Controlled Phase 2b PAGANINI Study

    The PAGANINI study evaluated the efficacy and safety of the selective P2X3 antagonist eliapixant in patients with refractory chronic cough (RCC).

    Peter V. Dicpinigaitis, Alyn H. Morice, Jaclyn A. Smith, Mandel R. Sher… in Lung (2023)

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    Article

    Combining Anti-IgE Monoclonal Antibodies and Oral Immunotherapy for the Treatment of Food Allergy

    Immunoglobulin E (IgE)-mediated food allergy is a real public health problem worldwide. The prevalence of food allergy is particularly high in children. Patients with food allergy experience high morbidity wit...

    Laurent Guilleminault, Marine Michelet… in Clinical Reviews in Allergy & Immunology (2022)

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    Article

    Obesity Predicts Treatment Response to Proton Pump Inhibitor Therapy in Patients with Chronic Cough

    Chronic cough management is challenging as this condition is often associated with multiple comorbidities, requiring a multidisciplinary diagnostic approach. Little is known about the characteristics of obese ...

    Mathilde Descazeaux, Danièle Brouquières, Alain Didier, Marianne Lescouzères… in Lung (2020)