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  1. Article

    Open Access

    Identification of a novel gene regulating amygdala-mediated fear extinction

    Recent years have seen advances in our understanding of the neural circuits associated with trauma-related disorders, and the development of relevant assays for these behaviors in rodents. Although inherited f...

    Ozge Gunduz-Cinar, Emma Brockway, Lauren Lederle, Troy Wilcox… in Molecular Psychiatry (2019)

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  2. Article

    Open Access

    Quantitative trait loci for sensitivity to ethanol intoxication in a C57BL/6J × 129S1/SvImJ inbred mouse cross

    Individual variation in sensitivity to acute ethanol (EtOH) challenge is associated with alcohol drinking and is a predictor of alcohol abuse. Previous studies have shown that the C57BL/6J (B6) and 129S1/SvImJ...

    Elissa J. Chesler, Aaron Plitt, Daniel Fisher, Benita Hurd… in Mammalian Genome (2012)

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  3. Article

    Genetic Strain Differences in Learned Fear Inhibition Associated with Variation in Neuroendocrine, Autonomic, and Amygdala Dendritic Phenotypes

    Mood and anxiety disorders develop in some but not all individuals following exposure to stress and psychological trauma. However, the factors underlying individual differences in risk and resilience for these...

    Marguerite C Camp, Kathryn P MacPherson, Lauren Lederle… in Neuropsychopharmacology (2012)

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  4. No Access

    Article

    Measuring anxiety- and locomotion-related behaviours in mice: a new way of using old tests

    Batteries of tests that are thought to measure different aspects of anxiety-related behaviour are used to characterise mice after genetic or pharmacological manipulation. However, because of the potentially co...

    Leanne M. Fraser, Richard E. Brown, Ahmed Hussin, Mara Fontana… in Psychopharmacology (2010)