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Article
Open AccessA cancer rainbow mouse for visualizing the functional genomics of oncogenic clonal expansion
Field cancerization is a premalignant process marked by clones of oncogenic mutations spreading through the epithelium. The timescales of intestinal field cancerization can be variable and the mechanisms drivi...
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Article
Open AccessA rapid and affordable screening platform for membrane protein trafficking
Membrane proteins regulate a diversity of physiological processes and are the most successful class of targets in drug discovery. However, the number of targets adequately explored in chemical space and the li...