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  1. Article

    Open Access

    Heat shock protein 90-targeted photodynamic therapy enables treatment of subcutaneous and visceral tumors

    Photodynamic therapy (PDT) ablates malignancies by applying focused near-infrared (nIR) light onto a lesion of interest after systemic administration of a photosensitizer (PS); however, the accumulation of exi...

    Kensuke Kaneko, Takuya Osada, Michael A. Morse, William R. Gwin in Communications Biology (2020)

  2. Article

    Open Access

    A cancer rainbow mouse for visualizing the functional genomics of oncogenic clonal expansion

    Field cancerization is a premalignant process marked by clones of oncogenic mutations spreading through the epithelium. The timescales of intestinal field cancerization can be variable and the mechanisms drivi...

    Peter G. Boone, Lauren K. Rochelle, Joshua D. Ginzel in Nature Communications (2019)