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Article
Open AccessHeat shock protein 90-targeted photodynamic therapy enables treatment of subcutaneous and visceral tumors
Photodynamic therapy (PDT) ablates malignancies by applying focused near-infrared (nIR) light onto a lesion of interest after systemic administration of a photosensitizer (PS); however, the accumulation of exi...
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Article
Open AccessA cancer rainbow mouse for visualizing the functional genomics of oncogenic clonal expansion
Field cancerization is a premalignant process marked by clones of oncogenic mutations spreading through the epithelium. The timescales of intestinal field cancerization can be variable and the mechanisms drivi...