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Article
Spatial and temporal changes in tissue pH and ATP distribution in a new model of reversible focal forebrain ischemia in the rat
The effects of reversible middle cerebral artery occlusion on regional pH and ATP distribution were studied in a new stroke model in rats by a planimetric method. Thirty minutes of ischemia was followed by 2, ...
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The Effect of a Single-Dose Intravenous Vinpocetine on Chronic Stroke Patients. A PET Study
With the purpose of evaluating the effect of vinpocetine (Cavinton®), given in a single-dose infusion, on the cerebral metabolism and perfusion of chronic stroke patients, we measured in 12 patients with focal ce...
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Article
Miller Fisher syndrome
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Article
Translati onal challenges of neuroprotection strategy in ischemic stroke
Neuroprotection is a therapeutic strategy that attempts to save neurons from irreversible injury by modifying the effects of the ischemic cascade or facilitating reperfusion. Although numerous agents have show...
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Article
CCSVI and MS: a statement from the European Society of neurosonology and cerebral hemodynamics
To systematically review the ultrasonographic criteria proposed for the diagnosis of chronic cerebrospinal venous insufficiency (CCSVI). The authors analyzed the five ultrasonographic criteria, four extracrani...
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Article
Cerebrovascular hemodynamic changes in multiple sclerosis patients during head-up tilt table test: effect of high-dose intravenous steroid treatment
Demyelination in multiple sclerosis (MS) may cause damage to the vegetative nervous system. Our objective was to examine cerebral autoregulation assessed via blood pressure and cerebral blood flow velocity flu...
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Prognostic value of trans-thoracic echocardiography in patients with acute stroke and atrial fibrillation: findings from the RAF study
Anticoagulant therapy is recommended for the secondary prevention of stroke in patients with atrial fibrillation (AF). T he identification of patients at high risk for early recurrence, which are potential can...
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Article
Intravenous thrombolysis for ischemic stroke in the golden hour: propensity-matched analysis from the SITS-EAST registry
As there are scarce data regarding the outcomes of acute ischemic stroke (AIS) patients treated with intravenous thrombolysis (IVT) within 60 min from symptom onset (“golden hour”), we sought to compare outcom...
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Article
Open AccessAcute alcohol intoxication may cause delay in stroke treatment – case reports
The signs and symptoms of acute alcohol intoxication resemble those of vertebrobasilar stroke. Due to their shared symptoms including double vision, nystagmus, dysarthria, and ataxia, the differential diagnosi...
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Article
Open AccessRelationship between leukocyte counts and large vessel occlusion in acute ischemic stroke
Neuroinflammation plays an important role in the pathogenesis of acute ischemic stroke (AIS) and peripheral leukocyte counts have proved to be independent predictors of stroke severity and outcomes. Clinical s...
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Article
Open AccessEffects of acute alcohol consumption on neuronal activity and cerebral vasomotor response
In the majority of European countries, driving after drinking small-moderate amount of alcohol is legal. Motivated by our previous studies on cerebral hemodynamics, we aimed to study whether a small-moderate b...
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Carotid Disease: Usefulness of the Ultrasound
Our aim is to introduce the optimal setting of ultrasound devices and different methods for diagnosing of steno-occlusive diseases of carotid vessels. The authors also present a detailed description of morphol...
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Article
Open AccessReperfusion therapies in patients with acute ischaemic stroke and atrial fibrillation: data on safety and effectiveness from a multi-centre cohort study
Intravenous thrombolysis (IVT) and/or endovascular therapy (EVT) are currently considered best practices in acute stroke patients. Data regarding the efficacy and safety of reperfusion therapies in patients wi...