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Article
Open AccessReperfusion therapies in patients with acute ischaemic stroke and atrial fibrillation: data on safety and effectiveness from a multi-centre cohort study
Intravenous thrombolysis (IVT) and/or endovascular therapy (EVT) are currently considered best practices in acute stroke patients. Data regarding the efficacy and safety of reperfusion therapies in patients wi...
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Article
Open AccessPhylogenomics and the rise of the angiosperms
Angiosperms are the cornerstone of most terrestrial ecosystems and human livelihoods1,2. A robust understanding of angiosperm evolution is required to explain their rise to ecological dominance. So far, the angio...
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Article
Open AccessEvidence for postnatal neurogenesis in the human amygdala
The human amygdala is involved in processing of memory, decision-making, and emotional responses. Previous studies suggested that the amygdala may represent a neurogenic niche in mammals. By combining two dist...
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Article
Open AccessEffects of acute alcohol consumption on neuronal activity and cerebral vasomotor response
In the majority of European countries, driving after drinking small-moderate amount of alcohol is legal. Motivated by our previous studies on cerebral hemodynamics, we aimed to study whether a small-moderate b...
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Chapter
Carotid Disease: Usefulness of the Ultrasound
Our aim is to introduce the optimal setting of ultrasound devices and different methods for diagnosing of steno-occlusive diseases of carotid vessels. The authors also present a detailed description of morphol...
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Article
Open AccessA modified in vitro clot lysis assay predicts outcomes and safety in acute ischemic stroke patients undergoing intravenous thrombolysis
The outcome of intravenous thrombolysis using recombinant tissue plasminogen activator (rt-PA) is only favorable in ≈ 40% of acute ischemic stroke (AIS) patients. Moreover, in ≈ 6–8% of cases, intracerebral he...
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Article
Open AccessRelationship between leukocyte counts and large vessel occlusion in acute ischemic stroke
Neuroinflammation plays an important role in the pathogenesis of acute ischemic stroke (AIS) and peripheral leukocyte counts have proved to be independent predictors of stroke severity and outcomes. Clinical s...
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Article
Open AccessAcute alcohol intoxication may cause delay in stroke treatment – case reports
The signs and symptoms of acute alcohol intoxication resemble those of vertebrobasilar stroke. Due to their shared symptoms including double vision, nystagmus, dysarthria, and ataxia, the differential diagnosi...
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Article
Open AccessLow factor XIII levels after intravenous thrombolysis predict short-term mortality in ischemic stroke patients
In this observational study we investigated whether levels of factor XIII (FXIII) and its major polymorphisms affect the outcome of thrombolysis by recombinant tissue plasminogen activator (rtPA) in acute isch...
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Article
Intravenous thrombolysis for ischemic stroke in the golden hour: propensity-matched analysis from the SITS-EAST registry
As there are scarce data regarding the outcomes of acute ischemic stroke (AIS) patients treated with intravenous thrombolysis (IVT) within 60 min from symptom onset (“golden hour”), we sought to compare outcom...
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Article
Prognostic value of trans-thoracic echocardiography in patients with acute stroke and atrial fibrillation: findings from the RAF study
Anticoagulant therapy is recommended for the secondary prevention of stroke in patients with atrial fibrillation (AF). T he identification of patients at high risk for early recurrence, which are potential can...
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Article
Asymptomatic dissecting intimal lesions of common carotid arteries after carotid endarterectomy
Carotid endarterectomy is a standard treatment for symptomatic high-degree internal carotid artery stenosis. The aim of this article is to present possible intimal lesions after carotid endarterectomy. These l...
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Article
The age and genomic integrity of neurons after cortical stroke in humans
In this study, the authors use measures of carbon-14 in neuronal DNA from human stroke patient cortical tissue samples to show that, unlike previous studies done in rodents, they do not find any evidence of in...
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Article
Cerebrovascular hemodynamic changes in multiple sclerosis patients during head-up tilt table test: effect of high-dose intravenous steroid treatment
Demyelination in multiple sclerosis (MS) may cause damage to the vegetative nervous system. Our objective was to examine cerebral autoregulation assessed via blood pressure and cerebral blood flow velocity flu...
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Article
CCSVI and MS: a statement from the European Society of neurosonology and cerebral hemodynamics
To systematically review the ultrasonographic criteria proposed for the diagnosis of chronic cerebrospinal venous insufficiency (CCSVI). The authors analyzed the five ultrasonographic criteria, four extracrani...
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Article
Translati onal challenges of neuroprotection strategy in ischemic stroke
Neuroprotection is a therapeutic strategy that attempts to save neurons from irreversible injury by modifying the effects of the ischemic cascade or facilitating reperfusion. Although numerous agents have show...
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Article
Miller Fisher syndrome
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A Novel Method of Macropathologic and Arteriographic Examination of Carotid Specimens Obtained from Autopsy
Twenty carotid bifurcations were examined. During autopsy, carotid bifurcations were removed in toto. Unfixed carotids were ligated and cannulated for injection of an angiographic contrast medium followed by i...
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Article
Basic characteristics of hospital stroke services in Eastern Hungary
Stroke mortality is extremely high in Central-Eastern European countries. We report basic characteristics of a stroke unit in Eastern Hungary, including age and sex distribution; the proportion of transient is...
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The Effect of a Single-Dose Intravenous Vinpocetine on Chronic Stroke Patients. A PET Study
With the purpose of evaluating the effect of vinpocetine (Cavinton®), given in a single-dose infusion, on the cerebral metabolism and perfusion of chronic stroke patients, we measured in 12 patients with focal ce...
