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Article
Open AccessEarly histopathological changes of secondary degeneration in the spinal cord after total MCA territory stroke
Previous research has not demonstrated secondary degeneration of the spinal cord (SpC) motoneurons after cerebral infarct. The aim of the present study is to investigate the involvement of the anterior horn ce...
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Article
Open AccessAssessment of cerebral autoregulatory function and inter-hemispheric blood flow in older adults with internal carotid artery stenosis using transcranial Doppler sonography-based measurement of transient hyperemic response after carotid artery compression
Unhealthy vascular aging promotes atherogenesis, which may lead to significant internal carotid artery stenosis (CAS) in 5 to 7.5% of older adults. The pathogenic factors that promote accelerated vascular agin...
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Article
Open AccessCholinesterase inhibitors for the treatment of dementia: real-life data in Hungary
Dementia is one of the leading causes of death and disability in older population. Previous reports have shown that antidementia medications are associated with longer survival; nonetheless, the prevalence of ...
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Article
Open AccessImpact of COVID-19 on ischemic stroke care in Hungary
Data about the coronavirus disease 2019 (COVID-19) pandemic’s collateral damage on ischemic stroke (IS) care during the second epidemic wave in Central Europe are limited. We sought to evaluate the impact of t...
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Article
Open AccessDementia epidemiology in Hungary based on data from neurological and psychiatric specialty services
Hungary has a single-payer health insurance system covering 10 million inhabitants. All medical reports of the in- and outpatient specialist services were collected in the NEUROHUN database. We used ICD-10 cod...
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Article
Open AccessComparing extended versus standard time window for thrombectomy: caseload, patient characteristics, treatment rates and outcomes—a prospective single-centre study
New guidelines recommend thrombectomy up to 24 h in selected patients; however, the workload and benefit of extending time window are not known. We conducted a prospective single-centre study to determine the ...
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Article
Open AccessGenetic epidemiological characteristics of a Hungarian subpopulation of patients with Huntington’s disease
Recent advances in therapeutic options may prevent deterioration related to Huntington’s disease (HD), even at the pre-symptomatic stage. Be that as it may, a well-characterized patient population is essential...
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Article
Correction to: Assessment of cervical spine involvement in rheumatoid arthritis patients in the era of biologics: a real-life, cross-sectional MRI study
In the original article, the first author’s given name and family name were interchanged as provided by the authors in the original manuscript.
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Open AccessAssessment of cervical spine involvement in rheumatoid arthritis patients in the era of biologics: a real-life, cross-sectional MRI study
Cervical spine involvement may lead to severe complications in rheumatoid arthritis (RA). In the era of modern therapies, atlantoaxial subluxation (AAS) may be rare; however, it may still be detected in asympt...
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Article
Open AccessAssessment of cognitive function in female rheumatoid arthritis patients: associations with cerebrovascular pathology, depression and anxiety
We assessed cognitive function of female rheumatoid arthritis (RA) patients and analyze the determinants, with special focus on cerebrovascular morphology. Sixty methotrexate (MTX-) or biologic-treated RA pati...
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Article
Open AccessLate-onset Niemann–Pick disease type C overlap** with frontotemporal dementia syndromes: a case report
The diagnosis of adult-onset Niemann–Pick disease type C (NPC) could be difficult because its primary symptoms [dementia and vertical supranuclear gaze palsy (VSGP)] are mainly seen in neurodegenerative dement...
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Article
Open AccessPurinergic Signalling in Parkinson’s Disease: A Multi-target System to Combat Neurodegeneration
Parkinson’s disease (PD) is the second most common neurodegenerative disorder, characterized by progressive loss of dopaminergic neurons that results in characteristic motor and non-motor symptoms. l-3,4 dihydrox...
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Article
Open AccessThe validation of the Hungarian version of the ID-migraine questionnaire
Despite its high prevalence, migraine remains underdiagnosed and undertreated. ID-Migraine is a short, self-administrated questionnaire, originally developed in English by Lipton et al. and later validated in ...
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Article
Open AccessA case report of isolated distal upper extremity weakness due to cerebral metastasis involving the hand knob area
Unilateral weakness of an upper extremity is most frequently caused by traumatic nerve injury or compression neuropathy. In rare cases, lesion of the central nervous system may result in syndromes suggesting p...
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Article
Increased frequency of temporal acoustic window failure in rheumatoid arthritis: a manifestation of altered bone metabolism?
Assessment of intracranial vessels includes transcranial Doppler (TCD). TCD performance requires intact temporal acoustic windows (TAW). Failure of TAW (TAWF) is present in 8–20% of people. There have been no ...
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Open AccessAssessment of intracranial vessels in association with carotid atherosclerosis and brain vascular lesions in rheumatoid arthritis
Stroke has been associated with rheumatoid arthritis (RA). We assessed patients with RA and healthy control subjects by transcranial Doppler (TCD), carotid ultrasonography and brain magnetic resonance imaging ...
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Article
Anomalous equivalent potential temperature: an atmospheric feature predicting days with higher risk for fatal outcome in acute ischemic stroke—a preliminary study
Acute stroke is a life-threatening condition. Fatal outcome is related to risk factors, some of these affected by climatic changes. Forecasting potentially harmful atmospheric processes may therefore be of pra...
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Article
Living standard is related to microregional differences in stroke characteristics in Central Europe: the Budapest Districts 8–12 Project
To test whether str oke features relate to living standard within one city by comparing 2 districts.
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Article
Health state utilities for migraine based on attack frequency: a time trade-off study
This study aims to evaluate health state utilities for migraine based on attack frequency from a mixed population sample consisting of migraineurs and non-migraineurs. A cross-sectional questionnaire survey wa...
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Article
COL4A2 mutation causing adult onset recurrent intracerebral hemorrhage and leukoencephalopathy
Type IV collagen α1 and α2 chains form heterotrimers that constitute an essential component of basement membranes. Mutations in COL4A1, encoding the α1 chain, cause a multisystem disease with prominent cerebrova...
