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Article
In Vitro Study of the Cytotoxic and Immunotropic Effects of Molnupiravir and Favipiravir
The effects of the antiviral drugs molnupiravir and favipiravir on the viability of human embryonic lung cells and the production of cytokines by peripheral blood leukocytes of healthy donors and patients with...
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Article
Comparative Study of the Photocytotoxicity of Two Liposomal Forms of Chlorin E6
The effectiveness of two liposomal forms of the photosensitizer chlorin E6 differing in their method of preparation was compared. Two types of liposomes were obtained: one containing chlorin E6 in the lipid bi...
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Article
Liposomal form of Dexamethasone in Experimental Autoimmune Uveitis: Clinical and Immunological Effects
The effectiveness of liposomal dexamethasone in experimental autoimmune uveitis in rabbits was studied. An original liposomal form of dexamethasone and its official aqueous solution were compared. The liposoma...
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Article
Evaluation of Cellular Toxicity and Preclinical Safety of Using an Inhalable Liposomal form of Dexamethasone
A liposomal form of dexamethasone was obtained. Liposomal vesicles were formed. The efficiency of incorporating dexamethasone into the liposomes was 99.7%. The cytotoxicity of the obtained liposomes was studie...
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Article
Development of a Liposomal form of Furanocoumarins and Evaluation of its Antitumor Efficacy
A method for obtaining a liposomal form of furanocoumarins from Sosnowsky’s hogweed (SH) is proposed. Furanocoumarins were isolated from SH juice using column chromatography. HPLC analysis found that SH juice ...
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Article
Liposomal Composition Based on Hydroxyaluminum Phthalocyanine and Gold Nanoparticles for Combined Photodynamic and Photothermal Therapy
The present work was aimed at the synthesis, characterization, and cytotoxicity studies of a composition based on liposomes with hydroxyaluminum phthalocyanine (HAPC) and gold nanoparticles (GNP) for combined ...
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Article
Evaluation of the Effectiveness of Intra-Articular Administration of Dexamethasone Liposomal Form on a Model of Rheumatoid Arthritis in Rats
Joint diseases are frequently treated using intra-articular injection forms of drugs based on glucocorticosteroids, many of which have disadvantages that hinder increasing their effectiveness. Liposomal forms ...
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Article
Comparative Efficacies of Doxorubicin Complexes with Dextran Phosphate and Dextran Sulfate for Intracavity Chemotherapy of Zajdela Ascitic Hepatoma in Rats
The efficacies of doxorubicin (Dox) complexes with carbohydrate polymers dextran phosphate (DP) and dextran sulfate (DS) in rats with grafted Zajdela ascitic hepatoma were studied in two series of experiments....
