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Article
Comparative Efficacies of Doxorubicin Complexes with Dextran Phosphate and Dextran Sulfate for Intracavity Chemotherapy of Zajdela Ascitic Hepatoma in Rats
The efficacies of doxorubicin (Dox) complexes with carbohydrate polymers dextran phosphate (DP) and dextran sulfate (DS) in rats with grafted Zajdela ascitic hepatoma were studied in two series of experiments....
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Article
Design of Nanosomal Form of Aprotinin
Liposomes containing aprotinin were produced by the phase inversion technique and purified by gel filtration. Aprotinin inclusion was assessed fluorescence labeling of the protein. The size of obtained liposom...
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Article
Method Development for Quantitative Determination of Ormustine in Biological Fluids by High Performance Liquid Chromatography with Mass-Spectrometric Detection
An HPLC method over a Kromasil C18 reversed-phase column with mass spectrometric detection and EtOH:NH4OAc (10:90) mobile phase was developed for quantitative determination of the antitumor drug ormustine in biol...
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Article
Efficiency of Combining Free and Polymer-Immobilized Prospidin with Doxorubicin for Treatment of Zajdel Ascites Hepatoma in Rats
The antitumor activity and side effects of the drug combinations prospidin + doxorubicin and prospidin hydrogel + doxorubicin were studied in rats with transplanted Zajdel ascites hepatoma. Test animals were d...
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Article
Automated system for generalization of streamgage major hydrologic characteristics over a long-term period
A new automated system of engineering hydrologic calculations is considered. It is intended for generalization of hydrologic observations data over a long-term period and for practical use in projecting and de...
