Skip to main content

2 Result(s)

within L C Spender Remove this filter

and

  1. Article

    TGF-β induces apoptosis in human B cells by transcriptional regulation of BIK and BCL-XL

    Transforming growth factor-β (TGF-β) potently induces apoptosis in Burkitt's lymphoma (BL) cell lines and in explanted primary human B lymphocytes. The physiological relevance and mechanism of TGF-β-mediated apop...

    L C Spender, D I O'Brien, D Simpson, D Dutt, C D Gregory… in Cell Death & Differentiation (2009)

    Download PDF (1680 KB) View Article

  2. No Access

    Article

    TGF-β-mediated activation of RhoA signalling is required for efficient V12HaRas and V600EBRAF transformation

    Transforming growth factor β-1 (TGF-β) acts as both a tumour suppressor and a tumour promoter in a context-dependent manner. The tumour-promoting activities of TGF-β are likely to result from a combination of ...

    Y M Fleming, G J Ferguson, L C Spender, J Larsson, S Karlsson, B W Ozanne… in Oncogene (2009)