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  1. Article

    Correction to: KSR1 regulates BRCA1 degradation and inhibits breast cancer growth

    A Correction to this paper has been published: https://doi.org/10.1038/s41388-021-01759-9

    J. Stebbing, H. Zhang, Y. Xu, L. C. Lit, A. R. Green, A. Grothey, Y. Lombardo… in Oncogene (2021)

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    Article

    KSR1 regulates BRCA1 degradation and inhibits breast cancer growth

    Kinase suppressor of Ras-1 (KSR1) facilitates signal transduction in Ras-dependent cancers, including pancreatic and lung carcinomas but its role in breast cancer has not been well studied. Here, we demonstrat...

    J Stebbing, H Zhang, Y Xu, L C Lit, A R Green, A Grothey, Y Lombardo… in Oncogene (2015)

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    Article

    The regulatory roles of phosphatases in cancer

    The relevance of potentially reversible post-translational modifications required for controlling cellular processes in cancer is one of the most thriving arenas of cellular and molecular biology. Any alterati...

    J Stebbing, L C Lit, H Zhang, R S Darrington, O Melaiu, B Rudraraju, G Giamas in Oncogene (2014)

  4. Article

    Open Access

    SILAC-based phosphoproteomics reveals an inhibitory role of KSR1 in p53 transcriptional activity via modulation of DBC1

    We have previously identified kinase suppressor of ras-1 (KSR1) as a potential regulatory gene in breast cancer. KSR1, originally described as a novel protein kinase, has a role in activation of mitogen-activa...

    H Zhang, Y Xu, A Filipovic, L C Lit, C-Y Koo, J Stebbing… in British Journal of Cancer (2013)

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    Article

    LMTK3 is implicated in endocrine resistance via multiple signaling pathways

    Resistance to endocrine therapy in breast cancer is common. With the aim of discovering new molecular targets for breast cancer therapy, we have recently identified LMTK3 as a regulator of the estrogen recepto...

    J Stebbing, A Filipovic, L C Lit, K Blighe, A Grothey, Y Xu, Y Miki, L W Chow… in Oncogene (2013)