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Article
Open AccessN-glycosylation of α1D-adrenergic receptor N-terminal domain is required for correct trafficking, function, and biogenesis
G protein-coupled receptor (GPCR) biogenesis, trafficking, and function are regulated by post-translational modifications, including N-glycosylation of asparagine residues. α1D-adrenergic receptors (α1D-ARs) – ke...
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Article
Open AccessScribble co-operatively binds multiple α1D-adrenergic receptor C-terminal PDZ ligands
Many G protein-coupled receptors (GPCRs) are organized as dynamic macromolecular complexes in human cells. Unraveling the structural determinants of unique GPCR complexes may identify unique protein:protein in...
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Article
Open AccessIndividual protomers of a G protein-coupled receptor dimer integrate distinct functional modules
Recent advances in proteomic technology reveal G-protein-coupled receptors (GPCRs) are organized as large, macromolecular protein complexes in cell membranes, adding a new layer of intricacy to GPCR signaling....
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Chapter and Conference Paper
Leveraging Wikipedia and Context Features for Clinical Event Extraction from Mixed-Language Discharge Summary
Unstructured clinical texts contain patients’ disease related narratives, but it is required elaborate work to mine the kind of information. Especially for the classification of semantic types of a clinical te...
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Chapter and Conference Paper
A Graph-Based Reliable User Classification
When some hot social issue or event occurs, it will significantly increase the number of comments and retweet on that day on Twitter. However, as the amount of SNS data increases, the noise also increases sync...
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Chapter and Conference Paper
Chinese and Korean Cross-Lingual Issue News Detection based on Translation Knowledge of Wikipedia
Cross-lingual issue news and analyzing the news content is an important and challenging task. The core of the cross-lingual research is the process of translation. In this paper, we focus on extracting cross-l...
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Chapter and Conference Paper
Extracting Social Events Based on Timeline and User Reliability Analysis on Twitter
When some hot social issue or event occurs, it will significantly increase the number of comments and retweet on that day on twitter. Generally, an event can be extracted by its term frequency but it is hard t...
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Chapter and Conference Paper
Follower Classification Based on User Behavior for Issue Clusters
Recently, Social Network Service has made a meteoric rise as means of communication to sharing important information. peoples discuss about social issues, especially in Twitter. Besides, unlike any other socia...
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Chapter and Conference Paper
Follower Classification through Social Network Analysis in Twitter
Through ‘Twitter’, one of the Social Network Service, people can have relationships by using ‘Follow’, a function of Twitter. Every user has different purposes, so there are various ‘Followers’, These Follower...
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Chapter and Conference Paper
Extracting Social Events Based on Timeline and Sentiment Analysis in Twitter Corpus
We propose a novel method for extracting social events based on timeline and sentiment analysis from social streams such as Twitter. When a big social issue or event occurs, it tends to dramatically increase i...
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Article
Human papillomavirus type 16 E6-specific antitumor immunity is induced by oral administration of HPV16 E6-expressing Lactobacillus casei in C57BL/6 mice
Given that local cell-mediated immunity (CMI) against the human papillomavirus type 16 E6 (HPV16 E6) protein is important for eradication of HPV16 E6-expressing cancer cells in the cervical mucosa, the HPV16 E...
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Article
Open AccessLactic acid bacteria affect serum cholesterol levels, harmful fecal enzyme activity, and fecal water content
Lactic acid bacteria (LAB) are beneficial probiotic organisms that contribute to improved nutrition, microbial balance, and immuno-enhancement of the intestinal tract, as well as lower cholesterol. Although pr...
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Article
Differential roles for the coactivators CBP and p300 on TCF/β-catenin-mediated survivin gene expression
The inhibitor of apoptosis (IAP) protein survivin is highly expressed in cancers, but not in normal differentiated tissues. TCF/β-catenin signaling has been reported to participate in the regulation of survivin t...
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Chapter and Conference Paper
Multilingual Story Link Detection Based on Event Term Weighting on Times and Multilingual Spaces
In this paper, we propose a novel approach for multilingual story link detection. Our approach uses features such as timelines and multilingual spaces for giving distinctive weights to terms that constitute li...
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Chapter and Conference Paper
Incorporating Virtual Relevant Documents for Learning in Text Categorization
This paper proposes a virtual relevant document technique in the learning phase for text categorization. The method uses a simple transformation of relevant documents, i.e. making virtual documents by combinin...
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Chapter and Conference Paper
Answer Extraction by Flexible Matching, Filtering, and Interpretation
This paper describes a Korean Question Answering (KorQuA) system. In our observation, QA systems need to consider these things to be more confident and intelligent: Terms in a text should be classified as the ...
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Chapter and Conference Paper
A Workbench for Acquiring Semantic Information and Constructing Dictionary for Compound Noun Analysis
This paper describes a workbench system for constructing a dictionary to interpret compound nouns, which integrates the acquisition of semantic information and interpretation of compound nouns. First, we extra...
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Article
Reexamination of sectional classification in far easternEuphorbia subgenusEsula (Euphorbiaceae) using morphological and phenolic data
Reexamining the classification proposed by Hurusawa, the phylogeny of Far EasternEuphorbia subgenusEsula was analyzed using thirteen morphological and seventeen phenolic compound data. These data were analyzed in...