5 Result(s)
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Article
Clonal analysis of early-stage bilateral papillary thyroid cancer identifies field cancerization
Bilaterality is a newly identified indicator for aggressive tumor behavior and poor outcome in papillary thyroid cancer. However, the clonal origin of these bilateral tumors remains unclear.
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Article
FP3: a novel VEGF blocker with antiangiogenic effects in vitro and antitumour effects in vivo
Vascular endothelial growth factor (VEGF) is a critical promoter of blood vessel growth during embryonic development and neovascularisation in tumours. VEGF serves as a logical target for antiangiogenic cancer...
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Article
Gallbladder carcinoma incidentally encountered during laparoscopic cholecystectomy: how to deal with it
Gallbladder cancer (GBC), characterised by rapid progression and a poor prognosis with a high mortality rate, is a complex disease to treat. Incidental gallbladder carcinoma (IGBC) is defined as carcinoma of t...
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Article
Aflibercept (VEGF Trap): one more double-edged sword of anti-VEGF therapy for cancer?
The use of vascular endothelial growth factor (VEGF)-targeted agents for treating cancer has increased dramatically over recent decades. These drugs provide considerable benefits in terms of progression-free (...
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Article
Patient-derived human tumour tissue xenografts in immunodeficient mice: a systematic review
Mouse cancer models have consistently been used to qualify new anticancer drugs in the development of human clinical trials. Rodent tumour models currently being used and which include transgenic tumour models...
