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Article
Open AccessDEEP MOVEMENT: Deep learning of movie files for management of endovascular thrombectomy
Treatment and outcomes of acute stroke have been revolutionised by mechanical thrombectomy. Deep learning has shown great promise in diagnostics but applications in video and interventional radiology lag behin...
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Article
Authorship in the Medical Humanities: Breaking Cross-field Boundaries or Maintaining Disciplinary Divides?
Medical humanities is a field which implies collaborative work across disciplines although the degree to which this actually occurs is unknown. Our purpose was to determine the degree of joint work in medical ...
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Cybersecurity in Healthcare
Embarking on a Medical Artificial Intelligence (AI) or Big Data project includes the integration of a myriad of medical devices, wireless technologies, data warehouses, and even social networks. Cybersecurity...
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Article
Open AccessImplementation of a patient-collected audio recording audit & feedback quality improvement program to prevent contextual error: stakeholder perspective
Using patient audio recordings of medical visits to provide clinicians with feedback on their attention to patient life context in care planning can improve health care delivery and outcomes, and reduce costs....
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Article
Open AccessAllostery of atypical modulators at oligomeric G protein-coupled receptors
Many G protein-coupled receptors (GPCRs) are therapeutic targets, with most drugs acting at the orthosteric site. Some GPCRs also possess allosteric sites, which have become a focus of drug discovery. In the M2 m...
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Open AccessRadiology artificial intelligence, a systematic evaluation of methods (RAISE): a systematic review protocol
There has been a recent explosion of research into the field of artificial intelligence as applied to clinical radiology with the advent of highly accurate computer vision technology. These studies, however, v...
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Article
Open AccessCalibration of HVI cotton elongation measurements
The strength of cotton fiber has been extensively studied and significant improvements in fiber strength have been made, but fiber elongation has largely been ignored, despite it contributing to the energy nee...
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Article
Open AccessCryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs
Allosteric modulators are highly desirable as drugs, particularly for G-protein-coupled receptor (GPCR) targets, because allosteric drugs can achieve selectivity between closely related receptors. The mechanis...
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Article
Structure-inspired design of β-arrestin-biased ligands for aminergic GPCRs
D2 dopamine receptor ligands biased for b-arrestin recruitment were developed based on a receptor homology model that identified conserved ligand contacts within the TM5 and EL2 regions as important for biased...
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Physical Properties of Cotton Fiber and Their Measurement
Cotton fiber is a highly variable natural product. The economic and industrial value of cotton is directly related to the physical properties of the fibers. In marketing cotton, the length, strength, color gra...
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Article
Design space for a solventless photocurable pharmaceutical coating
Solventless coating technologies can overcome many of the disadvantages associated with using solvents in pharmaceutical coating. A solventless photocurable film-coating system was investigated in which liquid...
