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Article
Open AccessModelling Spillover Effects on Informal Carers: The Carer QALY Trap
The provision of informal (unpaid) care can impose significant ‘spillover effects’ on carers, and accounting for these effects is consistent with the efficiency and equity objectives of health technology asses...
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Article
Open AccessTime and lexicographic preferences in the valuation of EQ-5D-Y with time trade-off methodology
In the valuation of EQ-5D-Y-3L, adult respondents are asked to complete composite time trade-off (cTTO) tasks for a 10-year-old child. Earlier work has shown that cTTO utilities elicited in such a child perspe...
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Article
Open AccessCorrection to: Time and lexicographic preferences in the valuation of EQ-5D-Y with time trade-off methodology
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Article
Open AccessAnalytical Considerations When Anchoring Discrete Choice Experiment Values Using Composite Time Trade-Off Data: The Case of EQ-5D-Y-3L
Discrete choice experiments (DCEs) are becoming increasingly used to elicit preferences for children’s health states. However, DCE data need to be anchored to produce value sets, and composite time trade-off (...
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Article
Open AccessAdapting preference-based utility measures to capture the impact of cancer treatment-related symptoms
It is important that patient-reported outcome (PRO) measures used to assess cancer therapies adequately capture the benefits and risks experienced by patients, particularly when adverse event profiles differ a...
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Article
Open AccessAn exploration of methods for obtaining 0 = dead anchors for latent scale EQ-5D-Y values
Discrete choice experiments (DCEs) can be used to obtain latent scale values for the EQ-5D-Y, but these require anchoring at 0 = dead to meet the conventions of quality-adjusted life year (QALY) estimation. Th...
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Article
Open AccessEconomic evaluation of meningococcal vaccines: considerations for the future
In 2018, a panel of health economics and meningococcal disease experts convened to review methodologies, frameworks, and decision-making processes for economic evaluations of vaccines, with a focus on evaluati...
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Article
Open AccessA new method for valuing health: directly eliciting personal utility functions
Standard methods for eliciting the preference data upon which ‘value sets’ are based generally have in common an aim to ‘uncover’ people’s preferences by asking them to evaluate a subset of health states, then...
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Article
Valuing health at the end of life: an empirical study of public preferences
In 2009, the National Institute for Health and Clinical Excellence (NICE) issued supplementary advice to its Appraisal Committees to be taken into account when appraising life-extending, ‘end-of-life’ treatmen...
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Article
Open AccessOne-to-one versus group setting for conducting computer-assisted TTO studies: findings from pilot studies in England and the Netherlands
We compare two settings for administering time trade-off (TTO) tasks in computer-assisted interviews (one-to-one, interviewer-led versus group, self-complete) by examining the quality of the data generated in ...
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Article
Using QALYs in Cancer
The objective of this paper is to examine how well the QALY captures the health gains generated by cancer treatments, with particular focus on the methods for constructing QALYs preferred by the UK National In...
