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  1. Article

    Open Access

    Generation of uniform-sized multicellular tumor spheroids using hydrogel microwells for advanced drug screening

    Even though in vitro co-culture tumor spheroid model plays an important role in screening drug candidates, its wide applications are currently limited due to the lack of reliable and high throughput methods for g...

    Jong Min Lee, Da Yeon Park, Letao Yang, Eun-Joong Kim in Scientific Reports (2018)

  2. Article

    Open Access

    A biodegradable hybrid inorganic nanoscaffold for advanced stem cell therapy

    Stem cell transplantation, as a promising treatment for central nervous system (CNS) diseases, has been hampered by crucial issues such as a low cell survival rate, incomplete differentiation, and limited neur...

    Letao Yang, Sy-Tsong Dean Chueng, Ying Li, Misaal Patel in Nature Communications (2018)

  3. Article

    Open Access

    Nanotopography-mediated Reverse Uptake for siRNA Delivery into Neural Stem Cells to Enhance Neuronal Differentiation

    RNA interference (RNAi) for controlling gene expression levels using siRNA or miRNA is emerging as an important tool in stem cell biology. However, the conventional methods used to deliver siRNA into stem cell...

    Aniruddh Solanki, Shreyas Shah, Perry T. Yin, Ki-Bum Lee in Scientific Reports (2013)