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Open AccessrGO nanomaterial-mediated cancer targeting and photothermal therapy in a microfluidic co-culture platform
We developed the microfluidic co-culture platform to study photothermal therapy applications. We conjugated folic acid (FA) to target breast cancer cells using reduced graphene oxide (rGO)-based functional nan...
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Open AccessDual Stimuli-Triggered Nanogels in Response to Temperature and pH Changes for Controlled Drug Release
Poly-N-isopropyl acrylamide (PNIPAM) nanogels have been modified with different acrylic acid (AAc) contents for the efficient control of lower critical solution temperature (LCST). In this study, PNIPAM-co-AAc na...
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Facile Synthesis of Surfactant-Free Au Decorated Hollow Silica Nanoparticles for Photothermal Applications
We report herein a novel surfactant-free synthetic approach for hollow silica nanoparticles (HSN) loaded with Au nanocomposites (Au-HSN) to enhance photothermal properties. Transmission electron microscopy and...
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Open AccessGeneration of uniform-sized multicellular tumor spheroids using hydrogel microwells for advanced drug screening
Even though in vitro co-culture tumor spheroid model plays an important role in screening drug candidates, its wide applications are currently limited due to the lack of reliable and high throughput methods for g...
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Functional Graphene Oxide-Based Nanosheets for Photothermal Therapy
Cancer is one of the main causes of morbidity and mortality. Although a number of techniques are available for treatment, these methods still have a number of drawbacks, destroying healthy tissues and cells to...
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In vivo fluorescence imaging to assess early therapeutic response to tumor progression in a xenograft cancer model
Bioimaging technology plays an important role in assessment of therapeutic response in cancer therapy. Here, we report a non-invasive monitoring system for measuring tumor growth by in vivo fluorescence imaging. ...
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Open AccessCorrection: Corrigendum: Robust Type-specific Hemisynapses Induced by Artificial Dendrites
Scientific Reports 6: Article number: 24210; published online: 13 April 2016; updated: 20 June 2016 In the original version of this Article, an additional affiliation for Taek Dong Chung was omitted. The corre...
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Open AccessRobust Type-specific Hemisynapses Induced by Artificial Dendrites
Type-specificity of synapses, excitatory and inhibitory, regulates information process in neural networks via chemical neurotransmitters. To lay a foundation of synapse-based neural interfaces, artificial dend...
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Tissue response to implants of hyaluronic acid hydrogel prepared by microbeads
Hyaluronic acid hydrogels (HAHs) were synthesized by immersing the HA microbeads crosslinked with divinyl sulfone in phosphate buffered saline solution to assess the responses of tissues to the implant by mean...
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The impacts of open-mouth breathing on upper airway space in obstructive sleep apnea: 3-D MDCT analysis
Open-mouth breathing during sleep is a risk factor for obstructive sleep apnea (OSA) and is associated with increased disease severity and upper airway collapsibility. The aim of this study was to investigate ...
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Determination of glycated hemoglobin on the basis of spectral shifting from protein-dye interaction
A method for the detection of glycated proteins was developed on the basis of spectral shifting observed for 1-(4-Boronophenylazo)-2-hydroxy-3,6-naphthalene-disulfonic acid (azo-BA) dye. Hemoglobin A1c, a type of...
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Abstracts for the 6th Congress of Asian Sleep Research Society