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  1. Article

    Open Access

    Epiretinal Membrane Detection at the Ophthalmologist Level using Deep Learning of Optical Coherence Tomography

    Purpose: Previous deep learning studies on optical coherence tomography (OCT) mainly focused on diabetic retinopathy and age-related macular degeneration. We proposed a deep learning model that can identify epire...

    Ying-Chih Lo, Keng-Hung Lin, Henry Bair, Wayne Huey-Herng Sheu in Scientific Reports (2020)

  2. Article

    Open Access

    The association of dry eye syndrome and psychiatric disorders: a nationwide population-based cohort study

    Several previous studies reported a greater prevalence of dry eye syndrome (DES) among patients with psychiatric diseases. The aim of this study is to investigate the prevalence and risk factors of DES in pati...

    Chiao-Ying Liang, Wai-Man Cheang, Chun-Yuan Wang, Keng-Hung Lin in BMC Ophthalmology (2020)

  3. Article

    Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Valérie Turcot, Yingchang Lu, Heather M. Highland, Claudia Schurmann in Nature Genetics (2019)

  4. No Access

    Article

    Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

    The concentrations of high- and low-density-lipoprotein cholesterol and triglycerides are influenced by smoking, but it is unknown whether genetic associations with lipids may be modified by smoking. We conduc...

    Amy R. Bentley, Yun J. Sung, Michael R. Brown, Thomas W. Winkler in Nature Genetics (2019)

  5. Article

    Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    In the version of this article originally published, one of the two authors with the name Wei Zhao was omitted from the author list and the affiliations for both authors were assigned to the single Wei Zhao in...

    Valérie Turcot, Yingchang Lu, Heather M. Highland, Claudia Schurmann in Nature Genetics (2018)

  6. Article

    Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    In the published version of this paper, the name of author Emanuele Di Angelantonio was misspelled. This error has now been corrected in the HTML and PDF versions of the article.

    Valérie Turcot, Yingchang Lu, Heather M. Highland, Claudia Schurmann in Nature Genetics (2018)

  7. No Access

    Article

    Refining the accuracy of validated target identification through coding variant fine-map** in type 2 diabetes

    We aggregated coding variant data for 81,412 type 2 diabetes cases and 370,832 controls of diverse ancestry, identifying 40 coding variant association signals (P < 2.2 × 10−7); of these, 16 map outside known risk...

    Anubha Mahajan, Jennifer Wessel, Sara M. Willems, Wei Zhao in Nature Genetics (2018)

  8. No Access

    Article

    Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI), implicating pathways related to neuronal biology. Most GWAS loci represent clusters of common, noncoding variants fro...

    Valérie Turcot, Yingchang Lu, Heather M. Highland, Claudia Schurmann in Nature Genetics (2018)

  9. Article

    Open Access

    Detection of aqueous VEGF concentrations before and after intravitreal injection of anti-VEGF antibody using low-volume sampling paper-based ELISA

    Intraocular vascular endothelial growth factor (VEGF) levels play an important role in the pathogenesis of blindness-related diseases, such as age-related macular degeneration (AMD). Here, we aimed to develop ...

    Min-Yen Hsu, Yu-Chien Hung, De-Kuang Hwang, Shang-Chi Lin in Scientific Reports (2016)

  10. No Access

    Chapter and Conference Paper

    Feature Evaluation of Flow Limitation in Obstructive Sleep Apnea Cases

    Purpose: Obstructive Sleep Apnea(OSA) is an airway obstructed during sleep, due to intermittent respiratory arrest disease. Flow limitation is an important symptom of OSA, but the method of detecti...

    Kang ** Lin, Po-Chung Shih, Keng Hung Lin in The 15th International Conference on Biome… (2014)