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  1. No Access

    Article

    Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer

    Mathieu Lupien and colleagues report an enrichment of somatic mutations at the ESR1 cis-regulatory region in 7% of ESR1-positive breast cancers. They find that the activity of the recurrently mutated ESR1 enhance...

    Swneke D Bailey, Kinjal Desai, Ken J Kron, Parisa Mazrooei… in Nature Genetics (2016)

  2. Article

    Open Access

    Smoking status impacts microRNA mediated prognosis and lung adenocarcinoma biology

    Cigarette smoke is associated with the majority of lung cancers: however, 25% of lung cancer patients are non-smokers, and half of all newly diagnosed lung cancer patients are former smokers. Lung tumors exhib...

    Emily A Vucic, Kelsie L Thu, Larissa A Pikor, Katey SS Enfield, John Yee… in BMC Cancer (2014)

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  3. Article

    Open Access

    miRNA expression in human lung cancer and fetal lung: a comparative study

    Daiana D Becker-Santos, Kelsie L Thu, Patricia P Reis, Wendy P Robinson… in BMC Proceedings (2013)

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  4. No Access

    Article

    Integrating the multiple dimensions of genomic and epigenomic landscapes of cancer

    Advances in high-throughput, genome-wide profiling technologies have allowed for an unprecedented view of the cancer genome landscape. Specifically, high-density microarrays and sequencing-based strategies hav...

    Raj Chari, Kelsie L. Thu, Ian M. Wilson… in Cancer and Metastasis Reviews (2010)