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Chapter
Profiling Indolic Auxins Produced by the Strains of Aspergillus Using Novel HPTLC Technique
Fungi are recognized to have dealings with plants by several known mechanisms, one of which is through the production of phytohormones, auxins. Indole-3-acetate (IAA), indole-3-butyrate (IBA), and indole-3-pyr...
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Article
Examining the Utility of Coronary Artery Lack of Tapering and Perivascular Brightness in Incomplete Kawasaki Disease
In 2017, the AHA published revised guidelines for the diagnosis of Kawasaki disease (KD). In the absence of compelling data supporting or refuting the utility of lack of tapering (LT) and perivascular brightne...
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Chapter
Comparative Analysis of Cytotoxic Potential of Crude Extracts and Fractionated Isolates from Moringa oleifera Lam.
According to World Health Organization, most of the world’s population depends upon plants as an important element in primary healthcare systems. Ayurveda is India’s oldest indigenous medicine system of plant ...
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Article
Correction: Publisher Correction: ZNF143 provides sequence specificity to secure chromatin interactions at gene promoters
Nature Communications 6: Article number: 6186 (2015); Published: 3 February 2015; Updated: 10 April 2018 The original HTML version of this Article had an incorrect volume number of 2; it should have been 6. Th...
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Article
Correction: Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation
Nature Communications 5: Article number: 4999 (2014); Published: 23 September 2014; Updated: 10 April 2018 The original version of this Article had an incorrect volume number of 4; it should have been 5. This ...
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Article
Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer
Housheng Hansen He and colleagues perform an integrated analysis and identify 45 candidate long noncoding RNAs (lncRNAs) associated with prostate cancer risk. They further show that a prostate cancer risk alle...
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Article
Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer
Mathieu Lupien and colleagues report an enrichment of somatic mutations at the ESR1 cis-regulatory region in 7% of ESR1-positive breast cancers. They find that the activity of the recurrently mutated ESR1 enhance...
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Article
Open AccessDelayed methimazole-induced agranulocytosis in a 6-year old patient with Graves’ disease
Agranulocytosis is regarded as a rare side effect of methimazole (MMI) therapy that occurs in a dose dependent manner and that usually develops within the first 3–6 months of treatment. Although delayed develo...
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Article
ZNF143 provides sequence specificity to secure chromatin interactions at gene promoters
Chromatin interactions connect distal regulatory elements to target gene promoters guiding stimulus- and lineage-specific transcription. Few factors securing chromatin interactions have so far been identified....
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Article
Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation
GWAS have identified a breast cancer susceptibility locus on 2q35. Here we report the fine map** of this locus using data from 101,943 subjects from 50 case-control studies. We genotype 276 SNPs using the ‘i...
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Chapter and Conference Paper
Inferring Human Phenotype Networks from Genome-Wide Genetic Associations
Networks are commonly used to represent and analyze large and complex systems of interacting elements. We build a human phenotype network (HPN) of over 600 physical attributes, diseases, and behavioral traits;...
