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Open AccessRecombinant antithrombin attenuates acute kidney injury associated with rhabdomyolysis: an in vivo animal study
Rhabdomyolysis is characterized by the destruction and necrosis of skeletal muscle tissue, resulting in acute kidney injury (AKI). Recombinant antithrombin (rAT) has DNA repair and vascular endothelial-protect...
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Article
Open AccessEfficacy of combined use of Suvorexant and Ramelteon in preventing postoperative delirium: a retrospective comparative study
Suvorexant and ramelteon have been presented as useful for preventing postoperative delirium. Previous studies reported on the comparison with benzodiazepine hypnotics which have been known for the risk for in...
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Open AccessInvestigation of the relationship between intradialytic hypotension during hemodialysis and serum syndecan-1 concentration
Intradialytic hypotension and arrhythmias are complications of hemodialysis. They are associated with decreased intravascular volume due to reduced ultrafiltration volume, cardiac function, and arterial tone. ...
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Open AccessAcute exacerbation of idiopathic hypereosinophilic syndrome following asymptomatic coronavirus disease 2019: a case report
Previous research has suggested that some autoimmune diseases develop after the occurrence of coronavirus disease 2019. Hypereosinophilic syndrome is a rare disease presenting with idiopathic eosinophilia and ...
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Article
Myxoid type and non-myxoid type of intimal sarcoma in large vessels and heart: review of histological and genetic profiles of 20 cases
Intimal sarcoma is one of the most common and well-known primary malignant neoplasms of the aorta and heart. The authors reviewed cases of intimal sarcoma from histological, immunohistochemical and genetic pe...
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Open AccessSerum syndecan-1 reflects organ dysfunction in critically ill patients
Syndecan-1 (SDC-1) is found in the endothelial glycocalyx and shed into the blood during systemic inflammatory conditions. We investigated organ dysfunction associated with changing serum SDC-1 levels for earl...
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Open AccessPossible involvement of Syndecan-1 in the state of COVID-19 related to endothelial injury
The coronavirus infection 2019 (COVID-19) is associated with microvascular endothelial injury. Here, we report that syndecan-1, a component of endothelial glycocalyx, may reflect the disease state of COVID-19 ...
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Article
History of the development of antagonists for neuromuscular blocking agents
Muscle relaxation induced by neuromuscular blocking agents (NMBAs) is necessary for tracheal intubation and immobilization during surgery. Although acetylcholinesterase inhibitors have been successfully used a...
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Article
Muraminomicins, novel ester derivatives: in vitro and in vivo antistaphylococcal activity
Novel muraminomicin derivatives with antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA) were synthesized by esterification of the hydroxy group on the diazepanone ring of muraminomi...
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Open AccessCreation of haemoglobin A1c direct oxidase from fructosyl peptide oxidase by combined structure-based site specific mutagenesis and random mutagenesis
The currently available haemoglobin A1c (HbA1c) enzymatic assay consists of two specific steps: proteolysis of HbA1c and oxidation of the liberated fructosyl peptide by fructosyl peptide oxidase (FPOX). To dev...
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Open AccessEffect of high-flow high-volume-intermittent hemodiafiltration on metformin-associated lactic acidosis with circulatory failure: a case report
Metformin-associated lactic acidosis is a well-known life-threatening complication of metformin. We here report the case of a patient who developed metformin-associated lactic acidosis without organ manifestat...
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Radiation therapy for recurrent cardiac undifferentiated pleomorphic sarcoma after three operations
We report the case of a 57-year-old female suffering from recurrent malignant undifferentiated pleomorphic sarcoma of the left atrium. Metastasis to the posterior mediastinum was detected upon first presentati...
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Open Accessγ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis
Chronic inflammation-associated bone destruction, which is observed in rheumatoid arthritis (RA) and periodontitis, is mediated by excessive osteoclastogenesis. We showed previously that γ-glutamyltranspeptida...
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A case of complete clearance of chronic subdural hematoma accompanied by recurrent glioblastoma multiforme after administration of bevacizumab
The efficacy of bevacizumab, a humanized monoclonal antibody against vascular endothelial growth factor (VEGF), as an adjuvant therapy against various malignant tumors was recently established. Its pharmacolog...
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Open AccessA simple protein-energy wasting score for survival prediction of maintenance hemodialysis patients
The nutritional status of patients on maintenance hemodialysis (MHD) is a strong predictor of their survival. We assessed the reliability of a protein-energy wasting (PEW) score as a predictor of the survival ...
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Acute onset of mediastinal cystic lymphangioma in the puerperium
Lymphangioma is a benign congenital malformation develo** from the prenatal lymphatic vessels. Lymphangiomas are typically slow-growing and asymptomatic, but can occur throughout the body; there are few docu...
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Löeffler endocarditis and restrictive cardiomyopathy with biventricular apical thrombi
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Characterisation of non-calcified coronary plaque by 16-slice multidetector computed tomography: comparison with histopathological specimens obtained by directional coronary atherectomy
The efficacy of multidetector computed tomography (MDCT) for assessing coronary plaque composition has not been fully elucidated by comparison with histological findings. This study investigated the efficacy a...
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Three-dimensional echocardiography findings of biventricular thrombi complicated by cerebral embolism
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The development of rare earth element-labelled potassium-depleted clays for use as cohesive sediment tracers in aquatic environments
Understanding the transport behaviour of fine cohesive sediment is fundamental to the sustainable management of aquatic environments. Sediment tracing techniques are widely used for measuring the transport pat...
