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  1. No Access

    Article

    Riboflavin kinase couples TNF receptor 1 to NADPH oxidase

    Riboflavin kinase has been identified as a novel interacting partner for the death domain of receptor-1 for tumour necrosis factor (TNF-R1). It is required to recruit to and functionally couple p22phox to TNF-R1....

    Benjamin Yazdanpanah, Katja Wiegmann, Vladimir Tchikov, Oleg Krut… in Nature (2009)

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    Article

    Acid sphingomyelinase is a key regulator of cytotoxic granule secretion by primary T lymphocytes

    Granules containing perforin and granzymes are secreted from cytotoxic T lymphocytes. Krönke and co-workers find that acid sphingomyelase is needed for granule shrinkage just before exocytosis in this process.

    Jasmin Herz, Julian Pardo, Hamid Kashkar, Michael Schramm… in Nature Immunology (2009)