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    Article

    Can gene therapy be used to prevent cancer? Gene therapy for aldehyde dehydrogenase 2 deficiency

    Approximately 8% of the world population and 35–45% of East Asians are carriers of the hereditary disorder aldehyde dehydrogenase 2 (ALDH2) deficiency. ALDH2 plays a central role in the liver to metabolize eth...

    Rachel A. Montel, Carlos Munoz-Zuluaga, Katie M. Stiles in Cancer Gene Therapy (2022)

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    Gene therapy in a murine model of chronic eosinophilic leukemia-not otherwise specified (CEL-NOS)

    Chronic eosinophilic leukemia-not otherwise specified (CEL-NOS) is a rare, aggressive, fatal disease characterized by blood eosinophilia and dysfunction of organs infiltrated with eosinophils. Clinically, the ...

    Odelya E. Pagovich, Katie M. Stiles, Anna E. Camilleri, Anthony R. Russo in Leukemia (2022)