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  1. Article

    Open Access

    Evaluation of the rapid Idylla IDH1-2 mutation assay in FFPE glioma samples

    IDH1 and IDH2 mutational status is a critical biomarker with diagnostic, prognostic, and treatment implications in glioma. Although IDH1 p.R132H-specific immunohistochemistry is available, it is unable to identif...

    James P. Solomon, Carlos Munoz-Zuluaga, Cheyanne Slocum… in Diagnostic Pathology (2024)

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    Article

    Can gene therapy be used to prevent cancer? Gene therapy for aldehyde dehydrogenase 2 deficiency

    Approximately 8% of the world population and 35–45% of East Asians are carriers of the hereditary disorder aldehyde dehydrogenase 2 (ALDH2) deficiency. ALDH2 plays a central role in the liver to metabolize eth...

    Rachel A. Montel, Carlos Munoz-Zuluaga, Katie M. Stiles… in Cancer Gene Therapy (2022)