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Article
Quantitative trait loci for rolled leaf in a wheat EMS mutant from Jagger
Two QTLs with major effects on rolled leaf trait were consistently detected on chromosomes 1A (QRl.hwwg-1AS) and 5A (QRl.hwwg-5AL) in the field experiments.
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Article
Open AccessPopulation genomics of Puccinia graminis f.sp. tritici highlights the role of admixture in the origin of virulent wheat rust races
Puccinia graminis f.sp. tritici (Pgt) causes stem rust disease in wheat that can result in severe yield losses. The factors driving the evolution of its virulence and adaptation remain poorly characterized. We ut...
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Article
Open AccessGenomic variants affecting homoeologous gene expression dosage contribute to agronomic trait variation in allopolyploid wheat
Allopolyploidy greatly expands the range of possible regulatory interactions among functionally redundant homoeologous genes. However, connection between the emerging regulatory complexity and expression and p...
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Article
Open AccessDifferential chromatin accessibility landscape reveals structural and functional features of the allopolyploid wheat chromosomes
Our understanding of how the complexity of the wheat genome influences the distribution of chromatin states along the homoeologous chromosomes is limited. Using a differential nuclease sensitivity assay, we in...
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Article
Analysis of recombinant inbred line populations derived from wheat landraces to identify new genes for wheat stem sawfly resistance
Wheat landrace accessions were chosen from areas of the world with historical European wheat stem sawfly (Cephus pygmaeus L.) selection pressure to develop six recombinant inbred line (RIL) populations. Molecular...
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Article
Open AccessA haplotype map of allohexaploid wheat reveals distinct patterns of selection on homoeologous genomes
Bread wheat is an allopolyploid species with a large, highly repetitive genome. To investigate the impact of selection on variants distributed among homoeologous wheat genomes and to build a foundation for und...
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Article
Open AccessThe Drosophila melanogaster Genetic Reference Panel
A major challenge of biology is understanding the relationship between molecular genetic variation and variation in quantitative traits, including fitness. This relationship determines our ability to predict p...
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Article
Open AccessSystems genetics analysis of body weight and energy metabolism traits in Drosophila melanogaster
Obesity and phenotypic traits associated with this condition exhibit significant heritability in natural populations of most organisms. While a number of genes and genetic pathways have been implicated to play...
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Article
Systems genetics of complex traits in Drosophila melanogaster
Trudy Mackay and colleagues present a resource of 40 Drosophila melanogaster wild-derived inbred lines. The authors quantify genome-wide variation in transcript abundance for six ecologically relevant traits, cha...
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Article
Open AccessQuantitative genomics of locomotor behavior in Drosophila melanogaster
Locomotion is an integral component of most animal behaviors, and many human health problems are associated with locomotor deficits. Locomotor behavior is a complex trait, with population variation attributabl...
