7 Result(s)
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Katherine D Henderson
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Article
The efficacy of detecting variants with small effects on the Affymetrix 6.0 platform using pooled DNA
Genome-wide genoty** of a cohort using pools rather than individual samples has long been proposed as a cost-saving alternative for performing genome-wide association (GWA) studies. However, successful disea...
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Article
Open AccessThe association of polymorphisms in hormone metabolism pathway genes, menopausal hormone therapy, and breast cancer risk: a nested case-control study in the California Teachers Study cohort
The female sex steroids estrogen and progesterone are important in breast cancer etiology. It therefore seems plausible that variation in genes involved in metabolism of these hormones may affect breast cancer...
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Article
Body size and the risk of ovarian cancer by hormone therapy use in the California Teachers Study cohort
To investigate whether obesity and hormone therapy (HT) are associated with ovarian cancer risk among women in the California Teachers Study cohort.
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Article
Open AccessPregnancy-related factors and the risk of breast carcinoma in situand invasive breast cancer among postmenopausal women in the California Teachers Study cohort
Although pregnancy-related factors such as nulliparity and late age at first full-term pregnancy are well-established risk factors for invasive breast cancer, the roles of these factors in the natural history ...
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Physical Activity and Anthropometric Factors
Physical activity and certain anthropometric factors have been proposed as independent risk factors for breast cancer. Increased physical activity appears to be associated with decreased breast cancer risk, an...
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Physical Activity and Cancer
This chapter provides a synopsis of conclusions from existing epidemiologic literature on the association between physical activity and cancer risk and considers potential biological mechanisms underlying obse...
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Article
Open AccessGenetic polymorphisms of the GNRH1 and GNRHR genes and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)
Gonadotropin releasing hormone (GNRH1) triggers the release of follicle stimulating hormone and luteinizing hormone from the pituitary. Genetic variants in the gene encoding GNRH1 or its receptor may influence...
