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  1. No Access

    Protocol

    Analysis and Visualization of Protein Channels, Tunnels, and Pores with MOLEonline and ChannelsDB 2.0

    Channels, tunnels, and pores serve as pathways for the transport of molecules and ions through protein structures, thus participating to their functions. MOLEonline (https://mole.upol.cz

    Anna Špačková, Václav Bazgier, Tomáš Raček, David Sehnal in Protein Bioinformatics (2024)

  2. No Access

    Protocol

    Visualization and Analysis of Protein Structures with LiteMol Suite

    LiteMol suite is an innovative solution that enables near-instant delivery of model and experimental biomacromolecular structural data, providing users with an interactive and responsive experience in all mode...

    David Sehnal, Radka Svobodová, Karel Berka, Lukáš Pravda in Structural Bioinformatics (2020)

  3. No Access

    Protocol

    Automated Family-Wide Annotation of Secondary Structure Elements

    Secondary structure elements (SSEs) are inherent parts of protein structures, and their arrangement is characteristic for each protein family. Therefore, annotation of SSEs can facilitate orientation in the va...

    Adam Midlik, Ivana Hutařová Vařeková, Jan Hutař in Protein Supersecondary Structures (2019)

  4. No Access

    Article

    LiteMol suite: interactive web-based visualization of large-scale macromolecular structure data

    David Sehnal, Mandar Deshpande, Radka Svobodová Vařeková, Saqib Mir in Nature Methods (2017)

  5. No Access

    Article

    Novel thidiazuron-derived inhibitors of cytokinin oxidase/dehydrogenase

    Two new TDZ derivatives (HETDZ and 3FMTDZ) are very potent inhibitors of CKX and are promising candidates for in vivo studies.

    Jaroslav Nisler, David Kopečný, Radka Končitíková in Plant Molecular Biology (2016)

  6. Article

    Open Access

    Anatomy of enzyme channels

    Enzyme active sites can be connected to the exterior environment by one or more channels passing through the protein. Despite our current knowledge of enzyme structure and function, surprisingly little is know...

    Lukáš Pravda, Karel Berka, Radka Svobodová Vařeková, David Sehnal in BMC Bioinformatics (2014)