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  1. No Access

    Article

    Cryo-EM structure of a plant photosystem II supercomplex with light-harvesting protein Lhcb8 and α-tocopherol

    The heart of oxygenic photosynthesis is the water-splitting photosystem II (PSII), which forms supercomplexes with a variable amount of peripheral trimeric light-harvesting complexes (LHCII). Our knowledge of ...

    Monika Opatíková, Dmitry A. Semchonok, David Kopečný, Petr Ilík… in Nature Plants (2023)

  2. Article

    Open Access

    Monoterpenoid aryl hydrocarbon receptor allosteric antagonists protect against ultraviolet skin damage in female mice

    The human aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is a pivotal regulator of human physiology and pathophysiology. Allosteric inhibition of AhR was previously thought to ...

    Karolína Ondrová, Iveta Zůvalová, Barbora Vyhlídalová… in Nature Communications (2023)

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    Chapter

    Occurrence, Interconversion, and Perception of Topolins in Poplar

    The poplar species Populus × canadensis cv. Robusta was the first organism found to contain aromatic cytokinins. Screening of the content of aromatic cytokinins in leaves of 12 Populus species revealed that the c...

    David Kopečný, Dominika Kaczorová… in Meta-topolin: A Growth Regulator for Plant… (2021)

  4. No Access

    Article

    Characterization of five CHASE-containing histidine kinase receptors from Populus × canadensis cv. Robusta sensing isoprenoid and aromatic cytokinins

    Five poplar CHASE-containing histidine kinase receptors bind cytokinins and display kinase activities. Both endogenous isoprenoid and aromatic cytokinins bind to the receptors in live cell assays.

    Pavel Jaworek, Petr Tarkowski, Tomáš Hluska, Štěpán Kouřil, Ondřej Vrobel… in Planta (2019)

  5. No Access

    Article

    Occurrence and biosynthesis of cytokinins in poplar

    Isoprenoid and aromatic cytokinins occur in poplar as free compounds and constituents of tRNA, poplar isopentenyltransferases are involved in the production of isoprenoid cytokinins, while biosynthesis of thei...

    Pavel Jaworek, David Kopečný, David Zalabák, Marek Šebela, Štěpán Kouřil… in Planta (2019)

  6. No Access

    Article

    Novel thidiazuron-derived inhibitors of cytokinin oxidase/dehydrogenase

    Two new TDZ derivatives (HETDZ and 3FMTDZ) are very potent inhibitors of CKX and are promising candidates for in vivo studies.

    Jaroslav Nisler, David Kopečný, Radka Končitíková… in Plant Molecular Biology (2016)

  7. No Access

    Article

    N-acyl-ω-aminoaldehydes are efficient substrates of plant aminoaldehyde dehydrogenases

    Plant aminoaldehyde dehydrogenases (AMADHs, EC 1.2.1.19) belong to the family 10 of aldehyde dehydrogenases and participate in the metabolism of compounds related to amino acids such as polyamines or osmoprote...

    Jan Frömmel, Marek Šebela, Gabriel Demo, René Lenobel, Tomáš Pospíšil… in Amino Acids (2015)

  8. No Access

    Article

    Aldehyde dehydrogenase (ALDH) superfamily in plants: gene nomenclature and comparative genomics

    In recent years, there has been a significant increase in the number of completely sequenced plant genomes. The comparison of fully sequenced genomes allows for identification of new gene family members, as we...

    Chad Brocker, Melpomene Vasiliou, Sarah Carpenter, Christopher Carpenter… in Planta (2013)

  9. No Access

    Article

    Plant aminoaldehyde dehydrogenases oxidize a wide range of nitrogenous heterocyclic aldehydes

    The metabolic degradation of aldehydes is catalyzed by oxidoreductases from which aldehyde dehydrogenases (EC 1.2.1) comprise nonspecific or substrate-specific enzymes. The latter subset is represented, e.g., ...

    Jan Frömmel, Miroslav Soural, Martina Tylichová, David Kopečný, Gabriel Demo… in Amino Acids (2012)