-
Reference Work Entry In depth
Colorectal Cancer: Metastatic (Palliation)
Approximately 20% of patients with colorectal cancer present with established distant metastases. In most cases, the metastases are detectable with noninvasive imaging, and patients can be assigned to AJCC (Am...
-
Article
Unresectable Colorectal Cancer Synchronous Metastases: How to Manage the Primary Tumor
In patients with newly diagnosed colorectal cancer, a significant proportion of patients will present with disseminated disease. In the presence of a symptomatic primary tumor, resection may be required to all...
-
Chapter and Conference Paper
Evaluation of FastFlow Technology for Real-World Application
It is challenging to parallelize a real application without the knowledge of low level modes of parallelism available in the application, such as data parallelism and task parallelism. Until now, the parallel ...
-
Chapter and Conference Paper
DASH: Data Structures and Algorithms with Support for Hierarchical Locality
DASH is a realization of the PGAS (partitioned global address space) model in the form of a C++ template library. Operator overloading is used to provide global-view PGAS semantics without the need for a custo...
-
Chapter and Conference Paper
Leveraging MPI-3 Shared-Memory Extensions for Efficient PGAS Runtime Systems
The relaxed semantics and rich functionality of one-sided communication primitives of MPI-3 makes MPI an attractive candidate for the implementation of PGAS models. However, the performance of such implementat...
-
Article
Assessing Trends in Palliative Surgery for Extrahepatic Biliary Malignancies: A 15-Year Multicenter Study
Extrahepatic biliary malignancies are often diagnosed at an advanced stage. We compared patients with unresectable perihilar cholangiocarcinoma (PHCC) and gallbladder cancer (GBC) who underwent a palliative pr...
-
Article
A Comparison of Prognostic Schemes for Perihilar Cholangiocarcinoma
Although widely used, the 7th edition American Joint Committee on Cancer (AJCC) staging system for perihilar cholangiocarcinoma (PHC) may be limited. Disease-specific nomograms have been proposed as a better m...
-
Article
Modern Technical Approaches in Hepatic Surgery for Colorectal Metastases
The liver is the most common site of metastases from colorectal cancer and can present as synchronous or metachronous lesions. Successful, margin-negative resection of all liver metastases is associated with s...
-
Article
Defining the Chance of Statistical Cure Among Patients with Extrahepatic Biliary Tract Cancer
While surgery offers the best curative-intent treatment, many patients with biliary tract malignancies have poor long-term outcomes. We sought to apply a non-mixture cure model to calculate the cure fraction a...
-
Article
Gallbladder Cancer Presenting with Jaundice: Uniformly Fatal or Still Potentially Curable?
Jaundice as a presenting symptom of gallbladder cancer has traditionally been considered to be a sign of advanced disease, inoperability, and poor outcome. However, recent studies have demonstrated that a smal...
-
Article
Surgical Site Infection Is Associated with Tumor Recurrence in Patients with Extrahepatic Biliary Malignancies
Surgical site infections (SSI) are one of the most common complications after hepato-pancreato-biliary surgery. Infectious complications may lead to an associated immune-modulatory effect that inhibits the bod...
-
Article
The Effects of Travel Burden on Outcomes After Resection of Extrahepatic Biliary Malignancies: Results from the US Extrahepatic Biliary Consortium
Surgical resection of extrahepatic biliary malignancies has been increasingly centralized at high-volume tertiary care centers. While this has improved outcomes overall, increased travel burden has been associ...
-
Article
Ectopic, retroperitoneal adrenocortical carcinoma in the setting of Lynch syndrome
Adrenocortical carcinoma (ACC) is rare within the adult population. Ectopic ACC proves even rarer. This variant is formed by cortical fragments arrested during embryologic migration. ACC is also known to be as...
-
Article
Surgery Provides Long-Term Survival in Patients with Metastatic Neuroendocrine Tumors Undergoing Resection for Non-Hormonal Symptoms
Patients with metastatic neuroendocrine tumor (NET) often have an indolent disease course yet the outcomes for patients with metastatic NET undergoing surgery for non-hormonal (NH) symptoms of GI obstruction, ...
-
Article
Predictive Value of Chromogranin A and a Pre-Operative Risk Score to Predict Recurrence After Resection of Pancreatic Neuroendocrine Tumors
Chromogranin A (CgA) may be prognostic for patients with neuroendocrine tumors; however, the clinical utility of this test is unclear.
-
Article
Evaluating the ACS NSQIP Risk Calculator in Primary Pancreatic Neuroendocrine Tumor: Results from the US Neuroendocrine Tumor Study Group
In a changing health care environment where patient outcomes will be more closely scrutinized, the ability to predict surgical complications is becoming increasingly important. The American College of Surgeons...
-
Article
Adenocarcinoma Ex-Goblet Cell: a Retrospective Experience
Adenocarcinoma ex-goblet cell carcinoids (AGCCs) are rare appendiceal tumors with mixed neuroendocrine and glandular features. They tend to behave more aggressively than typical carcinoid tumors, affect younge...
-
Article
Appendiceal Neuroendocrine Tumors: Does Colon Resection Improve Outcomes?
Appendiceal neuroendocrine tumors (A-NETs) are rare neoplasms of the GI tract. They are typically managed according to tumor size; however, the impact of surgical strategy on the short- and long-term outcomes ...
-
Article
Recurrence of Non-functional Pancreatic Neuroendocrine Tumors After Curative Resection: A Tumor Burden-Based Prediction Model
Patients can experience recurrence following curative-intent resection of non-functional pancreatic neuroendocrine tumors (NF-pNETs). We sought to develop a nomogram to risk stratify patients relative to recur...
-
Article
Surgical Treatment of Neuroendocrine Tumors of the Terminal Ileum or Cecum: Ileocecectomy Versus Right Hemicolectomy
Simple ileocecectomy and right hemicolectomy are two potential operative approaches to treat patients with neuroendocrine neoplasm in the terminal ileum and/or cecum (IC-NENs). We sought to define the long-ter...
